MicroRNAs in papillary thyroid cancer: what is new in diagnosis and treatment

M Papaioannou, AG Chorti, A Chatzikyriakidou… - Frontiers in …, 2022 - frontiersin.org
Introduction Papillary thyroid cancer (PTC) accounts for up to 80% of thyroid malignancies.
New diagnostic and therapeutic options are suggested including innovative molecular …

Ubiquitin-modifying enzymes in thyroid cancer: Mechanisms and functions

X Xiong, BB Huang, Z Gan, W Liu, Y Xie, J Zhong… - Heliyon, 2024 - cell.com
Thyroid cancer is the most common malignant tumor of the endocrine system, and evidence
suggests that post-translational modifications (PTMs) and epigenetic alterations play an …

Prognostic biomarkers for predicting papillary thyroid carcinoma patients at high risk using nine genes of apoptotic pathway

C Arora, D Kaur, LD Naorem, GPS Raghava - PLoS One, 2021 - journals.plos.org
Aberrant expressions of apoptotic genes have been associated with papillary thyroid
carcinoma (PTC) in the past, however, their prognostic role and utility as biomarkers remains …

[HTML][HTML] Integration of transcriptome and cistrome analysis identifies RUNX1-target genes involved in pancreatic cancer proliferation

S Liu, F Xie, L Gan, T Peng, X Xu, S Guo, W Fu… - Genomics, 2020 - Elsevier
The extremely high proliferation rate of tumor cells contributes to pancreatic cancer (PC)
progression. Runt-related transcription factor 1 (RUNX1), a key factor in hematopoiesis that …

A three-microRNA panel in serum as novel biomarker for papillary thyroid carcinoma diagnosis

X Zou, F Gao, ZY Wang, H Zhang, QX Liu… - Chinese Medical …, 2020 - mednexus.org
Background: Accumulating evidence has revealed that circulating microRNAs (miRNAs) can
serve as non-invasive biomarkers for cancer diagnosis. This study aimed to identify …

MiR-514 attenuates proliferation and increases chemoresistance by targeting ATP binding cassette subfamily in ovarian cancer

S Xiao, M Zhang, C Liu, D Wang - Molecular Genetics and Genomics, 2018 - Springer
Cisplatin is one of the most popular chemotherapeutic drugs in treating ovarian cancer.
Resistance to cisplatin is a common clinical challenge that needs to be solved to increase its …

Functional loss of tumor suppressor genes detected by loss of heterozygosity, but not driver mutations, predicts aggressive lymph node status in papillary thyroid …

S Finkelstein, VA Timmaraju, S Samankan… - … -Research and Practice, 2023 - Elsevier
Background Recognizing aggressive tumor biology is essential to optimizing patient
management for papillary thyroid carcinomas (PTC). Aggressive lymph node (ALN) status is …

[HTML][HTML] The association of the BRAF-V600E mutation with the expression of the molecular markers in the primary tumor and metastatic tissue in papillary thyroid …

LV Spirina, SY Chizhevskaya, IV Kovaleva… - Asian Pacific Journal …, 2021 - ncbi.nlm.nih.gov
Objective: The aim of this study was investigation the AKT/mTOR signaling pathway
components, transcriptional and growth factors, as well as steroid hormone receptors and …

Dysregulation of microRNAs as the risk factor of lymph node metastasis in papillary thyroid carcinoma: Systematic review

R Laukiene, V Jakubkevicius… - Endokrynologia …, 2021 - journals.viamedica.pl
Papillary thyroid carcinoma (PTC) has an excellent prognosis with a relatively low mortality
rate, but a small portion of PTC patients suffer from an aggressive form of the disease. In …

甲状腺癌RNA 分子研究进展

林琳, 刘建华, 吴丽娜 - 肿瘤防治研究, 2019 - zlfzyj.com
甲状腺癌是内分泌系统中最常见的恶性肿瘤, 约占全身恶性肿瘤的1%. 目前在DNA
水平研究甲状腺癌的发病机制已经相对成熟, 但mRNA, miRNA, lncRNA, circRNA 等不同RNA …