High-dose vitamin C as a metabolic treatment of cancer: a new dimension in the era of adjuvant and intensive therapy
X Wang, J He, M Sun, S Wang, J Qu, H Shi… - Clinical and Translational …, 2024 - Springer
The anti-cancer mechanism of High-dose Vitamin C (HDVC) is mainly to participate in the
Fenton reaction, hydroxylation reaction, and epigenetic modification, which leads to the …
Fenton reaction, hydroxylation reaction, and epigenetic modification, which leads to the …
[HTML][HTML] Ecto-nOX disulfide-thiol exchanger 2 (ENOX2/tNOX) is a potential prognostic marker in primary malignant melanoma and may serve as a therapeutic target
M Böcker, E Chatziioannou, H Niessner, C Hirn… - International Journal of …, 2024 - mdpi.com
With an increasing incidence of malignant melanoma, new prognostic biomarkers for clinical
decision making have become more important. In this study, we evaluated the role of ecto …
decision making have become more important. In this study, we evaluated the role of ecto …
[HTML][HTML] Identification of Antioxidant Methyl Derivatives of Ortho-Carbonyl Hydroquinones That Reduce Caco-2 Cell Energetic Metabolism and Alpha-Glucosidase …
M Monroy-Cárdenas, C Almarza… - International Journal of …, 2024 - mdpi.com
α-glucosidase, a pharmacological target for type 2 diabetes mellitus (T2DM), is present in
the intestinal brush border membrane and catalyzes the hydrolysis of sugar linkages during …
the intestinal brush border membrane and catalyzes the hydrolysis of sugar linkages during …
Reactivation of nucleases with peroxidation damages induced by a menadione: ascorbate combination devastates human prostate carcinomas: ultrastructural aspects
J Gilloteaux, JM Jamison, JL Summers… - Ultrastructural …, 2024 - Taylor & Francis
Introduction Xenografts of androgen-independent human DU145 prostate metastatic
carcinomas implanted in nu/nu male mice have revealed a significant survival after a …
carcinomas implanted in nu/nu male mice have revealed a significant survival after a …
Tolerable treatment of glioblastoma with redox-cycling 'mitocans': a comparative study in vivo
Objectives: The present study describes a pharmacological strategy for the treatment of
glioblastoma by redoxcycling 'mitocans' such as quinone/ascorbate combination drugs …
glioblastoma by redoxcycling 'mitocans' such as quinone/ascorbate combination drugs …