Nutrition strategies promoting healthy aging: From improvement of cardiovascular and brain health to prevention of age-associated diseases

M Fekete, Z Szarvas, V Fazekas-Pongor, A Feher… - Nutrients, 2022 - mdpi.com
Background: An increasing number of studies suggest that diet plays an important role in
regulating aging processes and modulates the development of the most important age …

Nicotinamide Riboside, a Promising Vitamin B3 Derivative for Healthy Aging and Longevity: Current Research and Perspectives

A Biţă, IR Scorei, MV Ciocîlteu, OE Nicolaescu… - Molecules, 2023 - mdpi.com
Many studies have suggested that the oxidized form of nicotinamide adenine dinucleotide
(NAD+) is involved in an extensive spectrum of human pathologies, including …

Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women

Y Fukamizu, Y Uchida, A Shigekawa, T Sato… - Scientific reports, 2022 - nature.com
A decrease in the intracellular level of nicotinamide adenine dinucleotide (NAD+), an
essential coenzyme for metabolic activity, causes various age-related diseases and …

Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy …

S Yamaguchi, J Irie, M Mitsuishi, Y Uchino… - Endocrine …, 2024 - jstage.jst.go.jp
Obesity and aging are major risk factors for several life-threatening diseases. Accumulating
evidence from both rodents and humans suggests that the levels of nicotinamide adenine …

Metabolomic differentiation of tumor core versus edge in glioma

ME Baxter, HA Miller, J Chen, BJ Williams… - Neurosurgical …, 2023 - thejns.org
OBJECTIVE Gliomas exhibit high intratumor and interpatient heterogeneity. Recently, it has
been shown that the microenvironment and phenotype differ significantly between the …

Preclinical Characterization of Pharmacologic NAD+ Boosting as a Promising Therapeutic Approach in Rheumatoid Arthritis

C Perez‐Sanchez, A Escudero‐Contreras… - Arthritis & …, 2023 - Wiley Online Library
Objective We analyzed NAD+ metabolism in patients with rheumatoid arthritis (RA), its
association with disease activity and clinical outcomes of RA, and the therapeutic potential …

Adult patient diagnosed with NADSYN1 associated congenital NAD deficiency and analysis of NAD levels to be published in: European Journal of Medical Genetics

E Erbs, CL Brasen, AM Lund, M Rasmussen - European Journal of Medical …, 2023 - Elsevier
Introduction Nicotinamide adenine dinucleotide (NAD) is an essential cosubstrate/coenzyme
in multiple cellular redox processes and a substrate in several non-redox reactions …

[HTML][HTML] Improved Physical Performance Parameters in Patients Taking Nicotinamide Mononucleotide (NMN): A Systematic Review of Randomized Control Trials

J Wen, B Syed, S Kim, M Shehabat, U Ansari… - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Nicotinamide adenine dinucleotide (NAD+) is essential in the proper function of many
essential cellular processes in the human body. The purpose of this review is to investigate …

Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review

IM Gindri, G Ferrari, LPS Pinto, J Bicca… - American Journal …, 2024 - journals.physiology.org
Nicotinamide adenine dinucleotide (NAD+) is an essential pyridine nucleotide cofactor that
is present in cells and in several important biological processes, including oxidative …

Enhance Trial: Effects of NAD3® on Hallmarks of Aging and Clinical Endpoints of Health in Middle Aged Adults: A Subset Analysis Focused on Blood Cell NAD+ …

MD Roberts, SC Osburn, JS Godwin, BA Ruple… - Physiologia, 2022 - mdpi.com
Limited pre-clinical and clinical data suggest theacrine or theacrine-based supplements
modulate biological processes associated with lipid metabolism and aging. Herein, we …