Propanediol (1, 3-PD) production by fermentation of glycerol was described in 1881 but little
attention was paid to this microbial route for over a century. Glycerol conversion to 1, 3-PD …

Hydroxypropionic acid (3-HP) is a valuable platform chemical that can be produced
biologically from glucose or glycerol. This review article provides an overview and the …

Engineered metabolic pathways constructed from enzymes heterologous to the production
host often suffer from flux imbalances, as they typically lack the regulatory mechanisms …

Global energy and environmental problems have stimulated increased efforts towards
synthesizing biofuels from renewable resources,,. Compared to the traditional biofuel …

Engineering biosynthetic pathways in microbes for the production of complex chemicals and
pharmaceuticals is an attractive alternative to chemical synthesis. However, in transferring …

Over the past several decades, we have come to appreciate that healthy plants host, within
and on the surfaces of their tissues, endophytic and epiphytic fungi and bacteria that do not …

The power of a single engineered organism is limited by its capacity for genetic modification.
To circumvent the constraints of any singular microbe, a new frontier in synthetic biology is …

A transition toward sustainable bio-based chemical production is important for green growth.
However, productivity and yield frequently decrease as large-scale microbial fermentation …

The need for a sustainable resource supply, the rapid advances in plant biotechnology and
microbial genetics and the strategic shift of major chemical companies into the area of life …

As our fossil raw materials irrevocably diminish and environmental pressures build, a
progressive changeover of chemical industries to renewable feedstocks emerges as an …