Exploring ncRNA-mediated regulation of EGFR signalling in glioblastoma: From mechanisms to therapeutics

R Thapa, M Afzal, A Goyal, G Gupta, AA Bhat… - Life sciences, 2024 - Elsevier
Glioblastoma (GBM) is the most prevalent and deadly primary brain tumor type, with a
discouragingly low survival rate and few effective treatments. An important function of the …

CRISPR/Cas9-mediated gene therapy for glioblastoma: a scoping review

E Begagić, H Bečulić, N Đuzić, A Džidić-Krivić… - Biomedicines, 2024 - mdpi.com
This scoping review examines the use of CRISPR/Cas9 gene editing in glioblastoma (GBM),
a predominant and aggressive brain tumor. Categorizing gene targets into distinct groups …

[HTML][HTML] Glioblastoma multiforme

T Kanderi, S Munakomi, V Gupta - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
Objectives: Identify the epidemiology and pathophysiology of glioblastoma multiforme.
Assess strategies for the clinical and radiological evaluation of glioblastoma multiforme …

Progress in glioma stem cell research

V Ramar, S Guo, BA Hudson, M Liu - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma stands as the most aggressive form of adult brain cancer,
often resulting in a median survival of 14.6 months even following surgical intervention …

Augmented reality integration in skull base neurosurgery: A systematic review

E Begagić, H Bečulić, R Pugonja, Z Memić, S Balogun… - Medicina, 2024 - mdpi.com
Background and Objectives: To investigate the role of augmented reality (AR) in skull base
(SB) neurosurgery. Materials and Methods: Utilizing PRISMA methodology, PubMed and …

Challenges and Promise for Glioblastoma Treatment through Extracellular Vesicle Inquiry

GL Liguori - Cells, 2024 - mdpi.com
Glioblastoma (GB) is a rare but extremely aggressive brain tumor that significantly impacts
patient outcomes, affecting both duration and quality of life. The protocol established by …

Understanding the Significance of Hypoxia-Inducible Factors (HIFs) in Glioblastoma: A Systematic Review

E Begagić, H Bečulić, A Džidić-Krivić, S Kadić Vukas… - Cancers, 2024 - mdpi.com
Simple Summary This study explores hypoxia-inducible factors (HIFs) in glioblastoma
development, progression, and treatment. Reviewing 104 relevant studies, it highlights …

DNA nanomachine‐driven chemodynamic therapy against glioblastoma

X Li, Y Lan, X Fu, X Luo, J Chen, W Zhang, B Zuo… - …, 2024 - Wiley Online Library
Chemodynamic therapy (CDT) has shown promising antitumor effects in various malignant
tumors. However, its application for glioblastoma (GBM) is significantly hindered by the …

MR Imaging–Guided Focused Ultrasound—Clinical Applications in Managing Malignant Gliomas

H Chen, P Anastasiadis… - Magnetic Resonance …, 2024 - mri.theclinics.com
Malignant gliomas (MGs), including glioblastoma (GBM), are the most aggressive and
common forms of primary brain tumors in adults, presenting a significant challenge in neuro …

Fabrication of pH-responsive temozolomide (TMZ)-clacked tannic acid-altered zeolite imidazole nanoframeworks (ZIF-8) enhance anticancer activity and apoptosis …

C Ren, Q Tu, J He - Journal of Biomaterials Science, Polymer …, 2024 - Taylor & Francis
Glioma cancer is the primary cause of cancer-related fatalities globally for both men and
women. Traditional chemotherapy treatments for this condition frequently result in reduced …