Chemosensory signal transduction in Caenorhabditis elegans

DM Ferkey, P Sengupta, ND L'Etoile - Genetics, 2021 - academic.oup.com
Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

3DeeCellTracker, a deep learning-based pipeline for segmenting and tracking cells in 3D time lapse images

C Wen, T Miura, V Voleti, K Yamaguchi, M Tsutsumi… - Elife, 2021 - elifesciences.org
Despite recent improvements in microscope technologies, segmenting and tracking cells in
three-dimensional time-lapse images (3D+ T images) to extract their dynamic positions and …

The extraordinary AFD thermosensor of C. elegans

MB Goodman, P Sengupta - Pflügers Archiv-European Journal of …, 2018 - Springer
The nematode C. elegans exhibits complex thermal experience-dependent navigation
behaviors in response to environmental temperature changes of as little as 0.01° C over a> …

Deep learning-assisted comparative analysis of animal trajectories with DeepHL

T Maekawa, K Ohara, Y Zhang, M Fukutomi… - Nature …, 2020 - nature.com
A comparative analysis of animal behavior (eg, male vs. female groups) has been widely
used to elucidate behavior specific to one group since pre-Darwinian times. However, big …

A high-throughput behavioral screening platform for measuring chemotaxis by C. elegans

E Fryer, S Guha, LE Rogel-Hernandez… - Plos …, 2024 - journals.plos.org
Throughout history, humans have relied on plants as a source of medication, flavoring, and
food. Plants synthesize large chemical libraries and release many of these compounds into …

Sensory glia detect repulsive odorants and drive olfactory adaptation

D Duan, H Zhang, X Yue, Y Fan, Y Xue, J Shao, G Ding… - Neuron, 2020 - cell.com
Glia are typically considered as supporting cells for neural development and synaptic
transmission. Here, we report an active role of a glia in olfactory transduction. As a …

From architecture to evolution: multisensory evidence of decentralized emotion

JH Kryklywy, MR Ehlers, AK Anderson… - Trends in cognitive …, 2020 - cell.com
Emotional appraisal in humans is often considered a centrally mediated process by which
sensory signals, void of emotional meaning, are assessed by integrative brain structures …

Optimizing calcium detection methods in animal systems: a sandbox for synthetic biology

ES Li, MS Saha - Biomolecules, 2021 - mdpi.com
Since the 1970s, the emergence and expansion of novel methods for calcium ion (Ca2+)
detection have found diverse applications in vitro and in vivo across a series of model …

Concerted pulsatile and graded neural dynamics enables efficient chemotaxis in C. elegans

E Itskovits, R Ruach, A Kazakov, A Zaslaver - Nature communications, 2018 - nature.com
The ability of animals to effectively locate and navigate toward food sources is central for
survival. Here, using C. elegans nematodes, we reveal the neural mechanism underlying …

Redundant neural circuits regulate olfactory integration

W Yang, T Wu, S Tu, Y Qin, C Shen, J Li, MK Choi… - PLoS …, 2022 - journals.plos.org
Olfactory integration is important for survival in a natural habitat. However, how the nervous
system processes signals of two odorants present simultaneously to generate a coherent …