Numerical methods for the design and description of in vitro expansion processes of human mesenchymal stem cells

V Jossen, D Eibl, R Eibl - Digital Twins: Applications to the Design and …, 2020 - Springer
Human mesenchymal stem cells (hMSCs) are a valuable source of cells for clinical
applications (eg, treatment of acute myocardial infarction or inflammatory diseases) …

Population balance modelling of stem cell culture in 3D suspension bioreactors

E Bartolini, H Manoli, E Costamagna… - … Research and Design, 2015 - Elsevier
Growing and culturing stem cells in scalable quantities is of significant interest for both
research and therapy. In this paper, a computational population balance model is developed …

Adoption of Composite Bone Scaffold Loaded with Osteoporosis Drugs in the Repair of Bone Defects in an Osteoporotic Animal Model

H Tang, F Xue, H Yue, F Ji - Science of Advanced Materials, 2023 - ingentaconnect.com
To promote the differentiation of mesenchymal stem cells (MSCs) into osteogenic lineages,
icariin (ICA) was utilized. A composite scaffold material of ICA-bone powder/poly lactic acid …

[PDF][PDF] Population balance modelling of stem cell culture in 3D suspension bioreactors

M Hamad, H Manoli, M Irhimeh… - … ; Powering our future, 2014 - researchgate.net
Embryonic stem cells (ESCs) are pluripotent cells extracted from the developing mammalian
blastocyte (Sachinidis, Fleischmann et al. 2003; Bauwens, Yin et al. 2005; Laflamme, Gold …

Rôle des phénomènes de transport dans la mise au point de stratégies thérapeutiques de réparation osseuse

S Lemonnier - 2014 - theses.hal.science
L'objectif de ce travail de thèse est de dégager des méthodes et des outils permettant de
mieux comprendre le rôle joué par les phénomènes de transport (cellulaire, hydraulique et …

[PDF][PDF] Toward an Understanding of How Hypercapnia Affects Apoptosis in Human Promyeloblasts in 3D Suspension Culture Systems

M Hamad - 2017 - core.ac.uk
Basic biology teaches us that humans and all human cells breathe in oxygen and discard
carbon dioxide. We are also taught that excessive amounts of carbon dioxide are …

Multiscale modeling of three-dimensional cell cultures for type 2 diabetes studies

E Magrofuoco - 2011 - research.unipd.it
The pressing needs related to the processes of drug and therapy development for diseases
such as type 2 diabetes, have increased the demand for new technologies and protocols. In …

[PDF][PDF] Population balance modelling of stem cell culture in 3D

EBHM Eleonora - orthopaedics and traumatology, 2011 - tissueeng.net
Growing and culturing stem cells in scalable quantities is of significant interest for both
research and therapy. In this paper, a computational population balance model is developed …