Conspectus DNA-encoded library technology (DELT) is a new screening modality that
allows efficient, cost-effective, and rapid identification of small molecules with potential …

Photoredox catalysis has recently emerged as a powerful synthetic platform for accessing
complex chemical structures through non-traditional bond disconnection strategies that …

The synthesis of sulfides has been widely studied because this functional subunit is
prevalent in biomolecules and pharmaceuticals, as well as being a useful synthetic platform …

Excitation of photoactive electron donor–acceptor (EDA) complexes is an effective way to
generate radicals. Applications in a catalytic regime typically use catalytic donors. Herein …

C-Glycosides are important structures that are common to natural products and
pharmaceutical agents. Established methods for their synthesis involve the reaction of an …

DNA-encoded libraries have proven their tremendous value in the identification of new lead
compounds for drug discovery. To access libraries in new chemical space, many methods …

We report a conceptually distinct strategy for the synthesis of 1, 1-diarylalkanes and
triarylalkanes. Key to this approach is the use of light to simultaneously trigger (i) formation …

Transition-metal-catalyzed difunctionalization of olefins constitutes a fertile synthetic platform
for rapid access to complex molecules from bulk chemicals. However, substrates featuring …

Gem-difluoroalkenes and trifluoromethyl alkanes are pervasive in biologically active
molecules. Photo-catalyzed alkylation of α-CF 3-olefins provides a straightforward approach …

The photocatalyst-free electron donor–acceptor (EDA) complex photochemistry was
deemed to expand the potential of photodriven radical chemistry. Here, we report a cross …