[HTML][HTML] Therapeutic uses and pharmacological properties of garlic, shallot, and their biologically active compounds

P Mikaili, S Maadirad, M Moloudizargari… - Iranian journal of …, 2013 - ncbi.nlm.nih.gov
Objective (s): Garlic (Allium sativum L. family Liliaceae) is well known in Iran and its leaves,
flowers, and cloves have been used in traditional medicine for a long time. Research in …

Therapeutic role of garlic and vitamins C and E against toxicity induced by lead on various organs

S Mumtaz, S Ali, R Khan, HA Shakir, HM Tahir… - … Science and Pollution …, 2020 - Springer
Due to industrial and urban sewage, the metal contaminations in aquatic and terrestrial
environments are increasing day by day, especially in developing countries. Despite the …

Herb–drug interaction studies of herbs used in treatment of cardiovascular disorders—A narrative review of preclinical and clinical studies

AS Shaikh, AB Thomas, SS Chitlange - Phytotherapy research, 2020 - Wiley Online Library
About 70% of the world population is currently using medicinal herbs as complementary or
alternative medicine, which is increasing at a tremendous pace in both developed and …

Phytochemicals involved in mitigating silent toxicity induced by heavy metals

J Ceramella, AC De Maio, G Basile, A Facente, E Scali… - Foods, 2024 - mdpi.com
Heavy metals (HMs) are natural elements present in the Earth's crust, characterised by a
high atomic mass and a density more than five times higher than water. Despite their origin …

Pharmacokinetic interactions between herbal medicines and prescribed drugs: focus on drug metabolic enzymes and transporters

Q Meng, K Liu - Current Drug Metabolism, 2014 - ingentaconnect.com
Herbal medicines have been widely used for thousands of years, and now are gaining
continued popularity worldwide as a complementary or alternative treatment for a variety of …

Herbal medicines in Brazil: pharmacokinetic profile and potential herb-drug interactions

ALDA Mazzari, JM Prieto - Frontiers in Pharmacology, 2014 - frontiersin.org
A plethora of active compounds found in herbal medicines can serve as substrate for
enzymes involved in the metabolism of xenobiotics. When a medicinal plant is co …

Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood–brain barrier: relevance to CNS drug delivery

BJ Thompson, L Sanchez-Covarrubias… - Journal of Cerebral …, 2014 - journals.sagepub.com
Cerebral hypoxia and subsequent reoxygenation stress (H/R) is a component of several
diseases. One approach that may enable neural tissue rescue after H/R is central nervous …

Preclinical pharmacokinetics and tolerability of a novel meglumine‐based parenteral solution of topiramate and topiramate combinations for treatment of status …

C Rundfeldt, P Klein, D Boison, A Rotenberg… - …, 2023 - Wiley Online Library
Objective For an antiseizure medication (ASM) to be effective in status epilepticus (SE), the
drug should be administered intravenously (iv) to provide quick access to the brain …

Herb-drug interactions and their impact on pharmacokinetics: an update

W Cheng, K Xia, S Wu, Y Li - Current Drug Metabolism, 2023 - ingentaconnect.com
Herb medicine has a long history of application and is still used worldwide. With the
development of complementary and alternative medicine, the interaction between herb and …

Effects of green tea extract on atorvastatin pharmacokinetics in healthy volunteers

KS Abdelkawy, RM Abdelaziz… - European Journal of …, 2020 - Springer
Abstract Background and Objectives Green tea catechins were recently reported to inhibit
drug transporters such as organic anion-transporting polypeptides (OATPs) and metabolic …