Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update covering the period 1999–2000

DJ Harvey - Mass spectrometry reviews, 2006 - Wiley Online Library
This review describes the use of matrix‐assisted laser desorption/ionization (MALDI) mass
spectrometry for the analysis of carbohydrates and glycoconjugates and continues coverage …

Principles for multivalent ligand design

LL Kiessling, LE Strong, JE Gestwicki - 2000 - Elsevier
Publisher Summary This chapter focuses on principles for multivalent ligand design.
Multivalent interactions control a wide variety of cellular processes including cell surface …

Synthetic strategies for modified glycosphingolipids and their design as probes

CD Hunter, T Guo, G Daskhan, MR Richards… - Chemical …, 2018 - ACS Publications
The plasma membrane of cells contains a diverse array of lipids that provide important
structural and biological features. Glycolipids are typically a minor component of the cell …

Trivalent α-D-mannoside clusters as inhibitors of type-1 fimbriae-mediated adhesion of Escherichia coli: Structural variation and biotinylation

TK Lindhorst, S Kötter, U Krallmann-Wenzel… - Journal of the Chemical …, 2001 - pubs.rsc.org
Structural modifications of trivalent cluster mannosides are presented to further elucidate the
ligand preferences of the type-1 fimbrial lectin of Escherichia coli. Two types of variations are …

Model systems for studying polyvalent carbohydrate binding interactions

BT Houseman, M Mrksich - Host-Guest Chemistry: Mimetic Approaches to …, 2002 - Springer
This chapter describes several classes of model systems that have been used for studies of
polyvalent binding interactions between carbohydrates and proteins. This review is divided …

Use of O-glycosylation in total synthesis

H Pellissier - Tetrahedron, 2005 - Elsevier
Carbohydrates are the most abundant group of natural products and the role of sugars as
energy and biosynthetic resources (glycolysis, pentose phosphate cycle, etc.),'energy …

Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin

B Dhakal, A Mandhapati, P Eradi, S Park… - Journal of the …, 2024 - ACS Publications
The high affinity interaction between P-selectin glycoprotein ligand-1 (PSGL-1) and P-
selectin is mediated by a multimotif glycosulfopeptide (GSP) recognition domain consisting …

Calcium‐Dependent Carbohydrate–Carbohydrate Recognition between LewisX Blood Group Antigens

A Geyer, C Gege, RR Schmidt - … Chemie International Edition, 2000 - Wiley Online Library
During adhesion events in eukaryotic cells polyvalent carbohydrate–carbohydrate
recognition between LeX oligosaccharides plays a role. Clustering was mimicked by a …

Chemical and enzymatic synthesis of glycopolymers

SL Flitsch - Current Opinion in Chemical Biology, 2000 - Elsevier
The development of efficient, fast, flexible and general synthetic routes to glycopolymers is
an ongoing challenge and much progress has been made in recent years. Chemical …

Membrane adhesion via homophilic saccharide-saccharide interactions investigated by neutron scattering

E Schneck, B Demé, C Gege, M Tanaka - Biophysical journal, 2011 - cell.com
Solid-supported membrane multilayers doped with membrane-anchored oligosaccharides
bearing the LewisX motif (Le X lipid) were utilized as a model system of membrane …