Renal ischemia-reperfusion (IR) contributes to the development of ischemic acute renal
failure (ARF). Multi-factorial processes are involved in the development and progression of …

Iron overload as a highly risk factor, can be found in almost all human chronic and common
diseases. Iron chelators are often used to treat iron overload; however, patient adherence to …

Oxidative stress is considered to be the main cause of diabetic complications. As the role of
antioxidants in diabetes therapy is still underestimated, the aim of the present investigation …

While radiation hazards, due to free radical generation, present an enormous challenge for
biological and medical safety, melatonin is a potent scavenger of a variety of free radicals …

Reactive oxygen species (ROS) are suggested to participate in ischemia/reperfusion (I/R)
injury in the kidney. This study was designed to investigate the effect of rutin, a bioflavonoid …

Free radicals are involved in pathophysiology of ischemia/reperfusion injury (IRI). Melatonin
is a potent scavenger of reactive oxygen and nitrogen species. Thus, this study was …

There is increasing evidence to suggest that toxic oxygen radicals play an essential role in
the pathogenesis of ischemia/reperfusion (I/R) injury in the kidney. This study was designed …

Perioperative organ injury remains a medical, social and economic problem in cardiac
surgery. Patients with postoperative organ dysfunction have increases in morbidity, length of …

Purpose: To investigate whether melatonin (MLT) treatment has any protective effect on
unilateral ureteral obstruction (UUO)–induced kidney injury in rats. Materials and Methods …

Oxidative stress may have a role in liver damage after acute renal injury due to various
reasons such as ischemia reperfusion (IR). Diabetes mellitus (DM) is an important disease …