The immune system is highly time-of-day dependent. Pioneering studies in the 1960s were
the first to identify immune responses to be under a circadian control. Only in the last …

The role of IL-22 in intestinal health and disease | Journal of Experimental Medicine |
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Recent advances have contributed to a mechanistic understanding of neuroimmune
interactions in the intestine and revealed an essential role of this cross talk for gut …

The ability of the nervous system to sense environmental stimuli and to relay these signals to
immune cells via neurotransmitters and neuropeptides is indispensable for effective …

The multifaceted organization of the immune system involves not only patrolling
lymphocytes that constantly monitor antigen-presenting cells in secondary lymphoid organs …

Studies in recent years have uncovered the crucial function of neuroimmune interactions in
maintaining tissue homeostasis and protection. Immune and neuronal cells are often …

Group 3 innate lymphoid cells (ILC3s) are key players in intestinal homeostasis. ER stress is
linked to inflammatory bowel disease (IBD). Here, we used cell culture, mouse models, and …

The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …

The immune system is under control of the circadian clock. Many of the circadian rhythms
observed in the immune system originate in direct interactions between components of the …

Interactions between the mammalian host and commensal microbiota are enforced through
a range of immune responses that confer metabolic benefits and promote tissue health and …