Exosome-like systems: nanotechnology to overcome challenges for targeted cancer therapies

J García-Fernández, M de la Fuente Freire - Cancer Letters, 2023 - Elsevier
Exosomes are natural extracellular nanovesicles (30–150 nm in diameter) with the ability to
interact with and be taken up by specific cells. They are being explored as delivery systems …

Role of long non-coding RNAs (lncRNAs) in cancer: from subcellular localization to nanoparticles (NPs)-mediated targeted regulation

C Wei, Y Xu, Q Shen, R Li, X Xiao, PE Saw… - … Therapy-Nucleic Acids, 2023 - cell.com
Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides
in length that play crucial roles in cancer development and progression. With the rapid …

Kidney targeting peptide-modified biomimetic nanoplatforms for treatment of acute kidney injury

Z Huang, C Chun, X Li - Journal of Controlled Release, 2023 - Elsevier
The management of acute kidney injury (AKI) imposes a significant medical burden. Due to
the lack of effective drug transport vehicles, the administration of therapeutic agents for AKI …

Nano based-oncolytic viruses for cancer therapy

M Ajam-Hosseini, F Akhoondi, M Doroudian - Critical Reviews in Oncology …, 2023 - Elsevier
Oncolytic viruses (OV) are an attractive prospect due to their dual attack mechanism of direct
cell lysis and potentiation of an antitumor immune response. Various oncolytic viral vectors …

[HTML][HTML] Applications of biomimetic nanoparticles in breast cancer as a blueprint for improved next-generation cervical cancer therapy

L Farhoudi, SF Fobian, AL Oei, M Amin, MR Jaafari… - Nano Today, 2023 - Elsevier
Nanomedicines are innovative and promising, but lack a convincing clinical presence. Thus,
biomimetic nanoparticles (BMNPs) have been designed with functionalizations which …

[HTML][HTML] Recent Review on Biological Barriers and Host–Material Interfaces in Precision Drug Delivery: Advancement in Biomaterial Engineering for Better Treatment …

R Deshmukh, P Sethi, B Singh, J Shiekmydeen… - Pharmaceutics, 2024 - mdpi.com
Preclinical and clinical studies have demonstrated that precision therapy has a broad variety
of treatment applications, making it an interesting research topic with exciting potential in …

A small-molecule carrier for the intracellular delivery of a membrane-impermeable protein with retained bioactivity

X Ma, Z Zhang, A Barba-Bon, D Han, Z Qi, B Ge… - Proceedings of the …, 2024 - pnas.org
Intracellular protein delivery has the potential to revolutionize cell-biological research and
medicinal therapy, with broad applications in bioimaging, disease treatment, and genome …

[HTML][HTML] Biologics, theranostics, and personalized medicine in drug delivery systems

M Puccetti, M Pariano, A Schoubben… - Pharmacological …, 2024 - Elsevier
The progress in human disease treatment can be greatly advanced through the
implementation of nanomedicine. This approach involves targeted and cell-specific therapy …

Translational challenges and prospective solutions in the implementation of biomimetic delivery systems

Z Wang, X Wang, W Xu, Y Li, R Lai, X Qiu, X Chen… - Pharmaceutics, 2023 - mdpi.com
Biomimetic delivery systems (BDSs), inspired by the intricate designs of biological systems,
have emerged as a groundbreaking paradigm in nanomedicine, offering unparalleled …

[HTML][HTML] The potential of exosomes as a new therapeutic strategy for glioblastoma

LC Silva, F Branco, J Cunha, C Vitorino… - European Journal of …, 2024 - Elsevier
Glioblastoma (GBM) stands for the most common and aggressive type of brain tumour in
adults. It is highly invasive, which explains its short rate of survival. Little is known about its …