At ultra-high magnetic fields, such as 7T, MR imaging can noninvasively visualize the brain
in unprecedented detail and through enhanced contrast mechanisms. The increased SNR …

Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …

Purpose To compare a glycosaminoglycan chemical exchange saturation transfer
(gagCEST) imaging method, which enables sampling of the water signal as a function of the …

Osteoarthritis (OA) has become the most prevalent chronic disease of the elderly (1, 2) and
is an important cause of disability in our society with increasing incidence not only in the US …

Cartilage is one of the most essential tissues for healthy joint function and is compromised in
degenerative and traumatic joint diseases. There have been tremendous advances during …

Deuterium metabolic imaging (DMI) is a novel MR‐based method to spatially map
metabolism of deuterated substrates such as [6, 6'‐2H2]‐glucose in vivo. Compared with …

Osteoarthritis (OA) is the most common degenerative joint disease affecting articular
cartilage and other joint tissues, resulting in serious morbidity and large socioeconomic …

Minimally invasive and non‐destructive methods to quantify glycosaminoglycans (GAGs) in
articular cartilage extracellular matrix are of significant interest for the biochemical analysis …

PURPOSE: The purpose of this study is to evaluate the effect of contrast agent charge on the
contrast agent uptake ratio (CUR) in cartilage and to image the naturally occurring variations …

In this review article, techniques for sodium (23 Na) magnetic resonance imaging (MRI) are
presented. These techniques can also be used to image other nuclei with short relaxation …