Malaria is a major killer of children worldwide and the strongest known force for evolutionary
selection in the recent history of the human genome. The past decade has seen growing …

Malaria has been the pre-eminent cause of early mortality in many parts of the world
throughout much of the last five thousand years and, as a result, it is the strongest force for …

Malaria remains one of the most prevalent parasitoses worldwide. About 350 to 500million
febrile episodes are observed yearly in African children alone and more than 1million …

A genetic basis for interindividual variation in susceptibility to human infectious diseases has
been indicated by twin, adoptee, pedigree, and candidate gene studies. This has led to the …

Recent studies have shown that host genetics is an important determinant of the intensity of
infection and morbidity due to human helminths. Epidemiological studies of a number of …

Atopic diseases, including asthma, allergic rhinitis, and atopic dermatitis, are caused by
environmental factors in genetically predisposed individuals. Although the prevalence of …

A pilot study was conducted to determine if host genetic factors influence susceptibility and
outcomes in human filariasis. Using the candidate gene approach, a well-characterized …

The ancient disease of leprosy can cause severe disability and disfigurement and is still a
major health concern in many parts of the world. Only a subset of those individuals exposed …

The gene frequencies in 1993–1994 for haemoglobin S, haemoglobin C, alpha− 37
deletional thalassaemia, G6PDA−, HLA B∗ 5301 were estimated in Fulani, Mossi and …

Malaria, which is a major infectious disease worldwide, is caused by the Plasmodium
parasite, one of the longest-known parasites infecting humans. The malaria situation is …