Beyond chemoreception: diverse tasks of soluble olfactory proteins in insects

P Pelosi, I Iovinella, J Zhu, G Wang… - Biological Reviews, 2018 - Wiley Online Library
Odorant‐binding proteins (OBPs) and chemosensory proteins (CSPs) are regarded as
carriers of pheromones and odorants in insect chemoreception. These proteins are typically …

The review of current knowledge on neutrophil gelatinase-associated lipocalin (NGAL)

K Romejko, M Markowska, S Niemczyk - International journal of molecular …, 2023 - mdpi.com
Neutrophil gelatinase-associated lipocalin (NGAL) is a 25-kDa protein that is secreted
mostly by immune cells such as neutrophils, macrophages, and dendritic cells. Its production …

Lipocalin 2 expression promotes tumor progression and therapy resistance by inhibiting ferroptosis in colorectal cancer

N Chaudhary, BS Choudhary, SG Shah… - … Journal of Cancer, 2021 - Wiley Online Library
Lipocalin 2 is a siderophore‐binding protein that regulates iron homeostasis. Lipocalin 2
expression is elevated in multiple tumor types; however, the mechanisms that drive tumor …

Inflammation, NF-κB, and chronic diseases: how are they linked?

AB Kunnumakkara, B Shabnam, S Girisa… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Most chronic diseases, caused by lifestyle factors, appear to be linked to inflammation.
Inflammation is activated mechanistically, and nuclear factor-κB (NF-κB) is a significant …

More than a simple biomarker: the role of NGAL in cardiovascular and renal diseases

M Buonafine, E Martinez-Martinez, F Jaisser - Clinical science, 2018 - portlandpress.com
Neutrophil gelatinase-associated lipocalin (NGAL) is a small circulating protein that is highly
modulated in a wide variety of pathological situations, making it a useful biomarker of …

Iron and leukemia: new insights for future treatments

F Wang, H Lv, B Zhao, L Zhou, S Wang, J Luo… - Journal of Experimental …, 2019 - Springer
Iron, an indispensable element for life, is involved in all kinds of important physiological
activities. Iron promotes cell growth and proliferation, but it also causes oxidative stress …

Therapeutic genome editing of triple-negative breast tumors using a noncationic and deformable nanolipogel

P Guo, J Yang, J Huang… - Proceedings of the …, 2019 - National Acad Sciences
Triple-negative breast cancer (TNBC), which has the highest mortality rate of all breast
cancer, is in urgent need of a therapeutic that hinders the spread and growth of cancer cells …

Lipocalin-2 promotes pancreatic ductal adenocarcinoma by regulating inflammation in the tumor microenvironment

SB Gomez-Chou, AK Swidnicka-Siergiejko, N Badi… - Cancer research, 2017 - AACR
Abstract Lipocalin-2 (LCN2) promotes malignant development in many cancer types. LCN2
is upregulated in patients with pancreatic ductal adenocarcinoma (PDAC) and in obese …

[HTML][HTML] Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy

S Candido, SL Abrams, LS Steelman… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Various, diverse molecules contribute to the tumor microenvironment and influence invasion
and metastasis. In this review, the roles of neutrophil gelatinase-associated lipocalin (NGAL) …

Extracellular matrix remodeling facilitates obesity-associated cancer progression

M Kim, C Lee, J Park - Trends in cell biology, 2022 - cell.com
Obesity, a global public health concern, is an important risk factor for metabolic diseases
and several cancers. Fibro-inflammation in adipose tissues (ATs) is tightly associated with …