Venous thromboembolic disease genetics: from variants to function

M Underwood, C Bidlack, KC Desch - Journal of Thrombosis and …, 2024 - Elsevier
Venous thromboembolic disease (VTE) is a prevalent and potentially life-threatening
vascular disease including both deep vein thrombosis and pulmonary embolism. This …

Sex and statin-related genetic associations at the PCSK9 gene locus: results of genome-wide association meta-analysis

J Pott, A Kheirkhah, JR Gadin, ME Kleber… - Biology of sex …, 2024 - Springer
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key player of lipid
metabolism with higher plasma levels in women throughout their life. Statin treatment affects …

Genomic Landscape of Thrombosis Recurrence Risk Across Venous Thromboembolism Subtypes

G Munsch, F Thibord, OC Bezerra, JA Brody… - medRxiv, 2024 - medrxiv.org
Venous thromboembolism (VT) is a frequent (annual incidence of 1 to 2 per 1,000) and
potentially life-threatening (case-fatality rate up to 10%) disease. VT is associated with …