The what, where and how of delay activity

KK Sreenivasan, M D'Esposito - Nature reviews neuroscience, 2019 - nature.com
Working memory is characterized by neural activity that persists during the retention interval
of delay tasks. Despite the ubiquity of this delay activity across tasks, species and …

Norepinephrine versus dopamine and their interaction in modulating synaptic function in the prefrontal cortex

B Xing, YC Li, WJ Gao - Brain research, 2016 - Elsevier
Among the neuromodulators that regulate prefrontal cortical circuit function, the
catecholamine transmitters norepinephrine (NE) and dopamine (DA) stand out as powerful …

[图书][B] Anxious: The modern mind in the age of anxiety

J LeDoux - 2015 - books.google.com
Anxiety is the most prevalent psychiatric problem of our time. Decades of research have
gone into probing its mysteries and developing treatments. But what if we've been thinking …

Hyperexcited limbic neurons represent sexual satiety and reduce mating motivation

X Zhou, A Li, X Mi, Y Li, Z Ding, M An, Y Chen, W Li… - Science, 2023 - science.org
Transient sexual experiences can have long-lasting effects on behavioral decisions, but the
neural coding that accounts for this change is unclear. We found that the ejaculation …

Hyperpolarization-activated cyclic nucleotide-gated channels as drug targets for neurological disorders

B Santoro, MM Shah - Annual review of pharmacology and …, 2020 - annualreviews.org
The hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are voltage-gated
ion channels that critically modulate neuronal activity. Four HCN subunits (HCN1–4) have …

Cortical HCN channels: function, trafficking and plasticity

MM Shah - The Journal of physiology, 2014 - Wiley Online Library
The hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels belong to the
superfamily of voltage‐gated potassium ion channels. They are, however, activated by …

Genome-wide association of endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia (COGS) study

TA Greenwood, LC Lazzeroni, AX Maihofer… - JAMA …, 2019 - jamanetwork.com
Importance The Consortium on the Genetics of Schizophrenia (COGS) uses quantitative
neurophysiological and neurocognitive endophenotypes with demonstrated deficits in …

Alcohol consumption during adolescence in a mouse model of binge drinking alters the intrinsic excitability and function of the prefrontal cortex through a reduction in …

MC Salling, MJ Skelly, E Avegno, S Regan… - Journal of …, 2018 - Soc Neuroscience
Periodic episodes of excessive alcohol consumption (“binge drinking”) occur frequently
among adolescents, and early binge drinking is associated with an increased risk of alcohol …

Subcircuit-specific neuromodulation in the prefrontal cortex

N Dembrow, D Johnston - Frontiers in neural circuits, 2014 - frontiersin.org
During goal-directed behavior, the prefrontal cortex (PFC) exerts top-down control over
numerous cortical and subcortical regions. PFC dysfunction has been linked to many …

Cognitive neuroscience perspective on memory: overview and summary

S Sridhar, A Khamaj, MK Asthana - Frontiers in Human Neuroscience, 2023 - frontiersin.org
This paper explores memory from a cognitive neuroscience perspective and examines
associated neural mechanisms. It examines the different types of memory: working …