Deep learning-enabled virtual histological staining of biological samples
Histological staining is the gold standard for tissue examination in clinical pathology and life-
science research, which visualizes the tissue and cellular structures using chromatic dyes or …
science research, which visualizes the tissue and cellular structures using chromatic dyes or …
Digital histopathology by infrared spectroscopic imaging
R Bhargava - Annual Review of Analytical Chemistry, 2023 - annualreviews.org
Infrared (IR) spectroscopic imaging records spatially resolved molecular vibrational spectra,
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
A versatile deep learning architecture for classification and label-free prediction of hyperspectral images
Hyperspectral imaging is a technique that provides rich chemical or compositional
information not regularly available to traditional imaging modalities such as intensity …
information not regularly available to traditional imaging modalities such as intensity …
Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning
Systemic amyloidosis involves the deposition of misfolded proteins in organs/tissues,
leading to progressive organ dysfunction and failure. Congo red is the gold-standard …
leading to progressive organ dysfunction and failure. Congo red is the gold-standard …
Super-resolution far-field infrared imaging by photothermal heterodyne imaging
Infrared (IR) imaging provides chemical-specific information without the need for exogenous
labels. Conventional far-field IR imaging techniques are diffraction limited, which means an …
labels. Conventional far-field IR imaging techniques are diffraction limited, which means an …
Digital synthesis of histological stains using micro-structured and multiplexed virtual staining of label-free tissue
Histological staining is a vital step in diagnosing various diseases and has been used for
more than a century to provide contrast in tissue sections, rendering the tissue constituents …
more than a century to provide contrast in tissue sections, rendering the tissue constituents …
Is infrared spectroscopy ready for the clinic?
D Finlayson, C Rinaldi, MJ Baker - Analytical chemistry, 2019 - ACS Publications
Fourier transform-infrared spectroscopy (FT-IR) represents an attractive molecular
diagnostic modality for translation to the clinic, where comprehensive chemical profiling of …
diagnostic modality for translation to the clinic, where comprehensive chemical profiling of …
Simultaneous cancer and tumor microenvironment subtyping using confocal infrared microscopy for all-digital molecular histopathology
Histopathology based on spatial patterns of epithelial cells is the gold standard for clinical
diagnoses and research in carcinomas; although known to be important, the tissue …
diagnoses and research in carcinomas; although known to be important, the tissue …
[HTML][HTML] Emerging advances to transform histopathology using virtual staining
WW Dean - BME frontiers, 2020 - spj.science.org
In an age where digitization is widespread in clinical and preclinical workflows, pathology is
still predominantly practiced by microscopic evaluation of stained tissue specimens affixed …
still predominantly practiced by microscopic evaluation of stained tissue specimens affixed …
Multimodal imaging based on vibrational spectroscopies and mass spectrometry imaging applied to biological tissue: a multiscale and multiomics review
Molecular imaging has the potential to unearth important spatial and temporal relationships
in biological systems, including intercellular signaling as well as environmentally-cued …
in biological systems, including intercellular signaling as well as environmentally-cued …