Herbal medicine for the management of laxative activity

M Akram, M Thiruvengadam, R Zainab… - Current …, 2022 - ingentaconnect.com
Constipation is one of the most common and prevalent chronic gastrointestinal conditions
across the globe that is treated or managed through various methods. Laxatives are used for …

Based on network pharmacology and gut microbiota analysis to investigate the mechanism of the laxative effect of pterostilbene on loperamide-induced slow transit …

Z Yao, S Fu, B Ren, L Ma, D Sun - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Pterostilbene (PTE) is a natural polyphenol compound that has been proven to
improve intestinal inflammation, but its laxative effect on slow transit constipation (STC) has …

Associations between the oxidative balance score and constipation: a cross-sectional study of the NHANES, 2005–2010

Y Wang, J Li, W Sun, Y Tong, L Han, Z Jiang, W Xu… - BMC Public Health, 2024 - Springer
Abstracts Objective The oxidative balance score (OBS) reflects the overall burden of
oxidative stress in an individual, with a higher OBS indicating greater antioxidant exposure …

Soluble dietary fiber and cellulose from Saccharina japonica by-product ameliorate Loperamide-induced constipation via modulating enteric neurotransmitters, short …

J Cao, K Wang, N Li, L Zhang, L Qin, Y He… - International Journal of …, 2023 - Elsevier
The effects of soluble dietary fiber (SDF) and cellulose (IDF) from Saccharina japonica by-
product and their differences in improving constipation were further clarified in the present …

[HTML][HTML] Synbiotic yogurt containing konjac mannan oligosaccharides and Bifidobacterium animalis ssp. lactis BB12 alleviates constipation in mice by modulating the …

T Li, Q Yan, Y Wen, J Liu, J Sun, Z Jiang - Journal of Dairy Science, 2021 - Elsevier
Synbiotic dietary supplements, as an effective means of regulating the gut microbiota, may
have a beneficial effect on constipation. This study evaluated the effects of synbiotic yogurt …

Globularia alypum L. and Related Species: LC-MS Profiles and Antidiabetic, Antioxidant, Anti-Inflammatory, Antibacterial and Anticancer Potential

M Friščić, R Petlevski, I Kosalec, J Madunić, M Matulić… - Pharmaceuticals, 2022 - mdpi.com
Species from the genus Globularia L. have been used as healing agents for various
ailments, with utilization of Globularia alypum L. being most frequently reported. The aim of …

[HTML][HTML] Improving intestinal health and mitigating Loperamide-Induced constipation through the modulation of Aquaporin-3 expression, reduction of oxidative stress …

HY Lee, MK Hossain, SH Kim, PY Jeong… - Journal of Functional …, 2024 - Elsevier
Constipation, a prevalent gastrointestinal disorder characterized by infrequent bowel
movements and associated abdominal discomfort, poses a significant health concern. This …

[HTML][HTML] Preclinical experimental models for assessing laxative activities of substances/products under investigation: a scoping review of the literature

P Kongdang, D Pruksakorn… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Constipation is a common gastrointestinal problem worldwide. Its impact on health can
range from an unpleasant problem to being seriously troublesome. When lifestyle …

Zhishi Daozhi decoction alleviates constipation induced by a high-fat and high-protein diet via regulating intestinal mucosal microbiota and oxidative stress

X Peng, X Yi, N Deng, J Liu, Z Tan, Y Cai - Frontiers in Microbiology, 2023 - frontiersin.org
Background A growing body of evidence has demonstrated that a high-fat and high-protein
diet (HFHPD) causes constipation. This study focuses on understanding how the use of …

Integrated metagenomics and targeted-metabolomics analysis of the effects of phenylalanine on loperamide-induced constipation in rats

C Yang, X Bai, T Hu, X Xue, X Su, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Functional constipation is a common functional gastrointestinal disease. In our previous
study, we found that the gut microbiota structure was disordered and the level of …