The control of body and organ growth is essential for the development of adults with proper size and proportions, which is important for survival and reproduction. In animals, adult body …
In his classic book On Growth and Form, D'Arcy Thompson discussed the necessity of a physical and mathematical approach to understanding the relationship between growth and …
T Kim, D Hwang, D Lee, JH Kim, SY Kim… - The EMBO Journal, 2017 - embopress.org
Yes‐associated protein (YAP) and myocardin‐related transcription factor (MRTF) play similar roles and exhibit significant crosstalk in directing transcriptional responses to …
Organismal development is a complex process as it requires coordination of many aspects to grow into fit individuals, such as the control of body size and organ growth. Therefore, the …
G Huang, L Song, X Du, X Huang, F Wei - Nature Communications, 2023 - nature.com
The orchid mantises achieve camouflage with morphological modifications in body color and pattern, providing an interesting model for understanding phenotypic innovation …
X Sun, Y Ding, M Zhan, Y Li, D Gao, G Wang… - Nature …, 2019 - nature.com
The Hippo pathway plays an important role in organ development and adult tissue homeostasis, and its deregulation has been implicated in many cancers. The Hippo …
B Yao, Y Li, Z Wang, L Chen, M Poidevin, C Zhang… - Molecular cell, 2018 - cell.com
A ten-eleven translocation (TET) ortholog exists as a DNA N 6-methyladenine (6mA) demethylase (DMAD) in Drosophila. However, the molecular roles of 6mA and DMAD …
Cancer cells have abnormal gene expression profiles; however, to what degree these are chaotic or driven by structured gene regulatory networks is often not known. Here we studied …
D Blanco-Obregon, K El Marzkioui, F Brutscher… - Nature …, 2022 - nature.com
The control of organ size mainly relies on precise autonomous growth programs. However, organ development is subject to random variations, called developmental noise, best …