Redox signalling and regulation of the blood-brain barrier

E van Leeuwen, MB Hampton, LCD Smyth - The international journal of …, 2020 - Elsevier
Neurological disorders are associated with increased oxidative stress. Reactive oxidants
damage tissue and promote cell death, but it is apparent that oxidants can have more subtle …

MERCs. the novel assistant to neurotransmission?

OM Shirokova, PV Pchelin, IV Mukhina - Frontiers in Neuroscience, 2020 - frontiersin.org
In neuroscience, much attention is paid to intercellular interactions, in particular, to
synapses. However, many researchers do not pay due attention to the contribution of …

Astrocytic mitochondria in adult mouse brain slices show spontaneous calcium influx events with unique properties

TE Huntington, R Srinivasan - Cell Calcium, 2021 - Elsevier
Astrocytes govern critical aspects of brain function via spontaneous calcium signals in their
soma and processes. A significant proportion of these spontaneous astrocytic calcium …

Mechanistic multiscale modelling of energy metabolism in human astrocytes reveals the impact of morphology changes in Alzheimer's Disease

S Farina, V Voorsluijs, S Fixemer… - PLoS Computational …, 2023 - journals.plos.org
Astrocytes with their specialised morphology are essential for brain homeostasis as
metabolic mediators between blood vessels and neurons. In neurodegenerative diseases …