Gut–skin axis: current knowledge of the interrelationship between microbial dysbiosis and skin conditions

B De Pessemier, L Grine, M Debaere, A Maes… - Microorganisms, 2021 - mdpi.com
The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

Skin microbiota–host interactions

YE Chen, MA Fischbach, Y Belkaid - Nature, 2018 - nature.com
The skin is a complex and dynamic ecosystem that is inhabited by bacteria, archaea, fungi
and viruses. These microbes—collectively referred to as the skin microbiota—are …

TREM2 macrophages induced by human lipids drive inflammation in acne lesions

TH Do, F Ma, PR Andrade, R Teles… - Science …, 2022 - science.org
Acne affects 1 in 10 people globally, often resulting in disfigurement. The disease involves
excess production of lipids, particularly squalene, increased growth of Cutibacterium acnes …

The gut microbiome as a major regulator of the gut-skin axis

I Salem, A Ramser, N Isham… - Frontiers in microbiology, 2018 - frontiersin.org
The adult intestine hosts a myriad of diverse bacterial species that reside mostly in the lower
gut maintaining a symbiosis with the human habitat. In the current review, we describe the …

Potential role of the microbiome in acne: a comprehensive review

YB Lee, EJ Byun, HS Kim - Journal of clinical medicine, 2019 - mdpi.com
Acne is a highly prevalent inflammatory skin condition involving sebaceous sties. Although it
clearly develops from an interplay of multiple factors, the exact cause of acne remains …

From pathogenesis of acne vulgaris to anti-acne agents

TX Cong, D Hao, X Wen, XH Li, G He… - Archives of dermatological …, 2019 - Springer
Acne vulgaris is a cutaneous chronic inflammatory disorder with complex pathogenesis.
Four factors play vital roles in acne pathophysiology: hyperseborrhea and dysseborrhea …

A global perspective on the epidemiology of acne

JKL Tan, K Bhate - British Journal of Dermatology, 2015 - academic.oup.com
Acne is estimated to affect 9· 4% of the global population, making it the eighth most
prevalent disease worldwide. Epidemiological studies have demonstrated that acne is most …

Acne vulgaris

SM Tuchayi, E Makrantonaki, R Ganceviciene… - Nature reviews Disease …, 2015 - nature.com
Acne vulgaris is a chronic inflammatory disease—rather than a natural part of the life cycle
as colloquially viewed—of the pilosebaceous unit (comprising the hair follicle, hair shaft and …

Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies

J McLaughlin, S Watterson, AM Layton, AJ Bjourson… - Microorganisms, 2019 - mdpi.com
The anaerobic bacterium Propionibacterium acnes is believed to play an important role in
the pathophysiology of the common skin disease acne vulgaris. Over the last 10 years our …

[HTML][HTML] Vitamin D and the skin: Focus on a complex relationship: A review

WZ Mostafa, RA Hegazy - Journal of advanced research, 2015 - Elsevier
The “sunshine” vitamin is a hot topic that attracted ample attention over the past decades,
specially that a considerable proportion of the worldwide population are deficient in this …