A genetic basis of congenital isolated hypogonadotropic hypogonadism (CHH) can be
defined in almost 50% of cases, albeit not necessarily the complete genetic basis. Next …

Alzheimer's disease (AD) is a neurodegenerative disease that is characterized by
progressive memory decline and cognitive dysfunctions. Although the causes of AD have …

The development of Gonadotropin releasing hormone-1 (GnRH) neurons is important for a
functional reproduction system in vertebrates. Disruption of GnRH results in hypogonadism …

The positive regulatory (PR) domain containing 13 (PRDM13) putative chromatin modifier
and transcriptional regulator functions downstream of the transcription factor PTF1A, which …

Puberty is a developmental period characterized by a broad range of physiologic changes
necessary for the acquisition of adult sexual and reproductive maturity. These changes …

The development of the neuroendocrine system, including the hypothalamic–pituitary–
gonadal (HPG) axis, is sensitive to environmental impacts during critical developmental …

Gonadotropin releasing hormone (GnRH) neurons are hypothalamic neuroendocrine cells
that control sexual reproduction. During embryonic development, GnRH neurons migrate …

As obesity rates have risen around the world, so to have pregnancies complicated by
maternal obesity. Obesity during pregnancy is not only associated with negative health …

Semaphorins (SEMAs) are axon guidance factors that participate in axonal connections and
nerve system development. However, the functional roles of SEMAs in tumorigenesis are …

Neurovascular disorders, which involve the vascular and nervous systems, are common.
Research on such disorders usually focuses on either vascular or nervous components …