Sports drug testing using complementary matrices: advantages and limitations

M Thevis, H Geyer, L Tretzel, W Schänzer - Journal of pharmaceutical and …, 2016 - Elsevier
Today, routine doping controls largely rely on testing whole blood, serum, and urine
samples. These matrices allow comprehensively covering inorganic as well as low and high …

Asthma and exercise‐induced bronchoconstriction in athletes: diagnosis, treatment, and anti‐doping challenges

M Hostrup, ESH Hansen… - … journal of medicine …, 2024 - Wiley Online Library
Athletes often experience lower airway dysfunction, such as asthma and exercise‐induced
bronchoconstriction (EIB), which affects more than half the athletes in some sports, not least …

Annual banned‐substance review: analytical approaches in human sports drug testing

M Thevis, T Kuuranne, H Geyer… - Drug testing and …, 2017 - Wiley Online Library
There has been an immense amount of visibility of doping issues on the international stage
over the past 12 months with the complexity of doping controls reiterated on various …

Detection of asthma inhaler use via terahertz spectroscopy

DJ Tyree, MC Brothers, D Sim, L Flory, M Tomb… - ACS …, 2023 - ACS Publications
Inhaled medications are commonplace for administering bronchodilators, anticholinergics,
and corticosteroids. While they have a defined legitimate use, they are also used in sporting …

Model‐based meta‐analysis of salbutamol pharmacokinetics and practical implications for doping control

P Courlet, T Buclin, J Biollaz, I Mazzoni… - CPT …, 2022 - Wiley Online Library
Salbutamol was included in the prohibited list of the World Anti‐Doping Agency (WADA) in
2004. Although systemic intake is banned, inhalation for asthma is permitted but with …

Urine concentrations of vilanterol and its metabolites, GSK932009 and GW630200, after inhalation of therapeutic and supratherapeutic doses

M Østergaard, S Jessen, ESH Hansen… - Drug Testing and …, 2023 - Wiley Online Library
Abstract The 2023 Prohibited List issued by the World Anti‐Doping Agency (WADA) permits
athletes to inhale the beta2‐agonist vilanterol at a standard dose of 25 μg daily. However …

Quantitation of Formoterol, Salbutamol, and Salbutamol-4′-O-Sulfate in Human Urine and Serum via UHPLC-MS/MS

LC Harps, DA Bizjak, U Girreser, M Zügel… - Separations, 2023 - mdpi.com
The adrenergic beta-2 agonists formoterol and salbutamol are used for the treatment of
asthma and COPD but are also misused in sports competitions. Therefore, they are included …

Special considerations and perspectives for exercise-induced bronchoconstriction (EIB) in Olympic and other elite athletes

JS Zeiger, JM Weiler - The Journal of Allergy and Clinical Immunology: In …, 2020 - Elsevier
Diagnosing and treating elite and Olympic athletes with exercise-induced
bronchoconstriction has been well established. However, a subset of elite and Olympic …

Inhaled salbutamol induces leanness in well-trained healthy females but not males during a period of endurance training: a randomised controlled trial

M Hostrup, C Weinreich, M Bjerre… - ERJ Open …, 2023 - Eur Respiratory Soc
Introduction Many athletes use short-acting inhaled β2-agonists multiple times weekly
during training sessions to prevent exercise-induced bronchoconstriction, but it is unclear if …

Beyond bronchodilation: Illuminating the performance benefits of inhaled beta2‐agonists in sports

M Hostrup, S Jessen - … Journal of Medicine & Science in Sports, 2024 - Wiley Online Library
Given the prevalent use of inhaled beta2‐agonists in sports, there is an ongoing debate as
to whether they enhance athletic performance. Over the last decades, inhaled beta2 …