Cytotoxicity and chemotherapeutic potential of natural rosin abietane diterpenoids and their synthetic derivatives

C Faustino, Í Neto, P Fonte… - Current Pharmaceutical …, 2018 - ingentaconnect.com
Cancer is a major cause of morbidity and mortality worldwide. Chemotherapeutic agents
currently used in cancer treatment are associated with severe side effects and development …

Fatty acids and their amide derivatives from endophytes: new therapeutic possibilities from a hidden source

R Tanvir, A Javeed, Y Rehman - FEMS Microbiology letters, 2018 - academic.oup.com
Fatty acid and their amide derivatives are natural self-defense agents in plants. They have
been observed to be broadly bioactive against a variety of disease agents. The mechanism …

Smart “on-off” responsive drug delivery nanosystems for potential imaging diagnosis and targeted tumor therapy

F Liu, P Huang, D Huang, S Liu, Q Cao, X Dong… - Chemical Engineering …, 2019 - Elsevier
Cancer is one of the most concerned diseases in the world, where there is still no reported
specifically targeted drugs with high effect. In this study, mesoporous silica with a large pore …

Well Dispersive TiO2 Nanoparticles as Additives for Improving the Tribological Performance of Polyalphaolefin Gel Lubricant

R Zhang, D Qiao, X Liu, Z Guo, L Hu… - Industrial & Engineering …, 2018 - ACS Publications
The dispersibility of TiO2 nanoparticles in polyalphaolefin (PAO) are improved by the
interaction between the chemically modified TiO2 (denoted as TTO) and 1-methyl-2, 4-bis (N …

Syntheses and high selective cytotoxicity of dehydroabietylamine C-ring nitration derivatives

Z Gu, W Lu, H Xue, J Zhang, S Yang, L Xu - Fitoterapia, 2022 - Elsevier
To find more effective anticancer agents, a series of novel dehydroabietylamine (DA)
derivatives were synthesized, focusing on C-ring nitro modifications and C-18 imide …

Undescribed abietane-type diterpenoids and oleanane-type triterpenoids from the stem and branch of Tripterygium wilfordii

YL Hu, TQ Xu, HY Cheng, Y Liu, X Zhang, YB Zhang… - Phytochemistry, 2022 - Elsevier
Six undescribed abietane-type diterpenoids (tripterydinoids AF) and five undescribed
oleanane-type triterpenoids (tripterytrinoids AE) were obtained and determined from the …

Syntheses of C-ring modified dehydroabietylamides and their cytotoxic activity

J Wiemann, L Fischer, M Rohmer, R Csuk - European Journal of Medicinal …, 2018 - Elsevier
Due to their auspicious pharmacological efficacy as future drug candidates, natural products
have been attracting scientific interest for centuries. An interesting field of research concerns …

Synthesis and high antiproliferative activity of dehydroabietylamine pyridine derivatives in vitro and in vivo

F Zhao, W Lu, Y Xu, L Xu, J Zhang, X Sun… - Biochemical …, 2020 - portlandpress.com
Several bioactive dehydroabietylamine Schiff-bases (L1− L4), amides (L5− L11) and
complex CuL3 (NO3) 2, Cu (L5) 3, Co (L6) 2Cl2 had been synthesized successfully for …

Derivatisierung terpenoider Leitstrukturen

J Wiemann - 2019 - repo.bibliothek.uni-halle.de
Pflanzliche Naturstoffe bilden seit Jahrtausenden eine Grundlage für die Entdeckung und
Entwicklung von Arzneimitteln. Heutzutage werden die isolierten Wirkstoffe jedoch nur …

Салахутдинов Нариман Фаридович (RU)

КС Ковалева, ОС Олешко, ОИ Яровая… - Synthetic …, 2013 - elibrary.ru
Изобретение относится к применению 1, 1'-(гексан-1, 6-диил) бис (3-(((1R, 4aS, 10aR)-7-
изопропил-1, 4а-диметил-1, 2, 3, 4, 4а, 9, 10, 10а-октагидрофенантрен-1-ил) метил) …