Effect of protein–protein interactions on translational diffusion of spheroidal proteins

AM Kusova, AE Sitnitsky, VN Uversky… - International Journal of …, 2022 - mdpi.com
One of the commonly accepted approaches to estimate protein–protein interactions (PPI) in
aqueous solutions is the analysis of their translational diffusion. The present review article …

Resolving molecular diffusion and aggregation of antibody proteins with megahertz X-ray free-electron laser pulses

M Reiser, A Girelli, A Ragulskaya, S Das… - Nature …, 2022 - nature.com
X-ray free-electron lasers (XFELs) with megahertz repetition rate can provide novel insights
into structural dynamics of biological macromolecule solutions. However, very high dose …

Recent advances in synchrotron scattering methods for probing the structure and dynamics of colloids

T Narayanan - Advances in Colloid and Interface Science, 2024 - Elsevier
Recent progress in synchrotron based X-ray scattering methods applied to colloid science is
reviewed. An important figure of merit of these techniques is that they enable in situ …

Real-time swelling-collapse kinetics of nanogels driven by XFEL pulses

F Dallari, I Lokteva, J Möller, W Roseker, C Goy… - Science …, 2024 - science.org
Stimuli-responsive polymers are an important class of materials with many applications in
nanotechnology and drug delivery. The most prominent one is poly-N-isopropylacrylamide …

[HTML][HTML] Three-step colloidal gelation revealed by time-resolved x-ray photon correlation spectroscopy

A Jain, F Schulz, F Dallari, V Markmann… - The Journal of …, 2022 - pubs.aip.org
The gelation of PEGylated gold nanoparticles dispersed in a glycerol–water mixture is
probed in situ by x-ray photon correlation spectroscopy. Following the evolution of structure …

Analysis strategies for MHz XPCS at the European XFEL

F Dallari, M Reiser, I Lokteva, A Jain, J Möller… - Applied Sciences, 2021 - mdpi.com
The nanometer length-scale holds precious information on several dynamical processes
that develop from picoseconds to seconds. In the past decades, X-ray scattering techniques …

AI-NERD: Elucidation of relaxation dynamics beyond equilibrium through AI-informed X-ray photon correlation spectroscopy

JP Horwath, XM Lin, H He, Q Zhang… - Nature …, 2024 - nature.com
Understanding and interpreting dynamics of functional materials in situ is a grand challenge
in physics and materials science due to the difficulty of experimentally probing materials at …

NMR and dynamic light scattering give different diffusion information for short-living protein oligomers. Human serum albumin in water solutions of metal ions

AM Kusova, AK Iskhakova, YF Zuev - European Biophysics Journal, 2022 - Springer
Diffusive behavior of human serum albumin (HSA) in the presence of Mg2+ and Cu2+ ions
was studied by pulsed field gradient nuclear magnetic resonance (PFG NMR) and dynamic …

Operational experience with adaptive gain integrating pixel detectors at European XFEL

J Sztuk-Dambietz, V Rovensky, A Klujev, T Laurus… - Frontiers in …, 2024 - frontiersin.org
The European X-ray Free Electron Laser (European XFEL) is a cutting-edge user facility that
generates per second up to 27,000 ultra-short, spatially coherent X-ray pulses within an …

Thermal effects of beam profiles on X-ray photon correlation spectroscopy at megahertz X-ray free-electron lasers

Y Xu, M Sikorski, J Fan, H Jiang, Z Liu - Optics Express, 2022 - opg.optica.org
X-ray free-electron lasers (XFELs) with megahertz repetition rates enable X-ray photon
correlation spectroscopy (XPCS) studies of fast dynamics on microsecond and sub …