Characterizing network selectiveness to the dynamic spreading of neuropathological events in Alzheimer's disease

W Li, D Yang, C Yan, M Chen, Q Li… - Journal of …, 2022 - content.iospress.com
Background: Mounting evidence shows that the neuropathological burdens manifest
preference in affecting brain regions during the dynamic progression of Alzheimer's disease …

Pathology steered stratification network for subtype identification in Alzheimer's disease

E Xu, J Zhang, J Li, Q Song, D Yang, G Wu… - Medical …, 2024 - Wiley Online Library
Background Alzheimer's disease (AD) is a heterogeneous, multifactorial neurodegenerative
disorder characterized by three neurobiological factors beta‐amyloid, pathologic tau, and …

[PDF][PDF] Uncovering system vulnerability and criticality of human brain under evolving neuropathological events in alzheimer's disease

J Zhang, Q Liu, H Zhang, M Dai, Q Song… - arXiv preprint arXiv …, 2022 - researchgate.net
Despite the striking efforts in investigating neurobiological factors behind the acquisition of
beta-amyloid (A), protein tau (T), and neurodegeneration ([N]) biomarkers, the mechanistic …

Uncovering Diverse Mechanistic Spreading Pathways in Disease Progression of Alzheimer's Disease

Z Yu, Z Shi, T Dan, M Dere, M Kim… - Journal of …, 2023 - journals.sagepub.com
Background: The AT [N] research framework focuses on three major biomarkers in
Alzheimer's disease (AD): amyloid-β deposition (A), pathologic tau (T), and …

Uncovering the System Vulnerability and Criticality of Human Brain Under Dynamical Neuropathological Events in Alzheimer's Disease

J Zhang, Q Liu, H Zhang, M Dai… - Journal of …, 2023 - journals.sagepub.com
Background: Despite the striking efforts in investigating neurobiological factors behind the
acquisition of amyloid-β (A), protein tau (T), and neurodegeneration ([N]) biomarkers, the …