The purpose of this article is to provide a brief history of the development and application of
computer algorithms for the analysis and prediction of DNA binding sites. This problem can …

Phage T4 has provided countless contributions to the paradigms of genetics and
biochemistry. Its complete genome sequence of 168,903 bp encodes about 300 gene …

The iap gene in Escherichia coli is responsible for the isozyme conversion of alkaline
phosphatase. We analyzed the 1,664-nucleotide sequence of a chromosomal DNA segment …

A graphical method is presented for displaying the patterns in a set of aligned sequences.
The characters representing the sequence are stacked on top of each other for each position …

In order to obtain a novel binding protein against a chosen target, DNA molecules, each
encoding a protein comprising one of a family of similar potential binding domains and a …

Microbial fatty acid-derived fuels have emerged as promising alternatives to petroleum-
based transportation fuels. Here we report a modular engineering approach that …

In order to obtain a novel binding protein against a chosen target, DNA molecules, each
encoding a protein comprising one of a family of similar potential binding domains and a …

We have used a “Perceptron” algorithm to find a weighting function which distinguishes E.
coli translational initiation sites from all other sites in a library of over 78,000 nucleotides of …

The E. coli minicell locus (min6) was shown to code for three gene products (MinC, MinD,
and MinE) whose coordinate action is required for proper placement of the division spetum …

The complete nucleotide sequence of bacteriophage T7 DNA, 39,936 base-pairs, has been
determined by the techniques of Maxam & Gilbert. All previously known T7 genes and …