The burden of type 2 diabetes mellitus in states of the European Union and United Kingdom at the national and subnational levels: A systematic review

CA Soares Andrade, B Shahin, O Dede… - Obesity …, 2023 - Wiley Online Library
Type 2 diabetes mellitus (T2D) is a highly prevalent disease worldwide, with an equally
increased expenditure associated with it. We aimed to longitudinally evaluate the …

Triglyceride–glucose index (TyG index) in comparison with fasting plasma glucose improved diabetes prediction in patients with normal fasting glucose: the Vascular …

D Navarro-González, L Sánchez-Íñigo… - Preventive …, 2016 - Elsevier
Aims We evaluated the potential role of the triglyceride–glucose index (TyG index) as a
predictor of diabetes in a White European cohort, and compared it to fasting plasma glucose …

β Cell function and plasma insulin clearance in people with obesity and different glycemic status

B Mittendorfer, BW Patterson, GI Smith… - The Journal of …, 2022 - Am Soc Clin Investig
Background It is unclear how excess adiposity and insulin resistance affect β cell function,
insulin secretion, and insulin clearance in people with obesity. Methods We used a …

Triglyceride glucose-waist circumference, a novel and effective predictor of diabetes in first-degree relatives of type 2 diabetes patients: cross-sectional and …

S Zheng, S Shi, X Ren, T Han, Y Li, Y Chen… - Journal of translational …, 2016 - Springer
Background Body mass index (BMI), waist circumference (WC), visceral adiposity index
(VAI), triglyceride glucose index (TyG), TyG-BMI, and TyG-WC have been reported as …

Deteriorating beta cell function is the dominant determinant of progression from normal glucose tolerance to prediabetes/diabetes in young women following …

R Retnakaran, C Ye, CK Kramer, AJ Hanley… - Diabetologia, 2023 - Springer
Aims/hypothesis Excess adiposity, insulin resistance and beta cell dysfunction each
contribute to the development of prediabetes (impaired glucose tolerance and/or impaired …

Evolution of the diagnostic value of “the sugar of the blood”: hitting the sweet spot to identify alterations in glucose dynamics

F Magkos, DN Reeds… - Physiological reviews, 2022 - journals.physiology.org
In this paper, we provide an overview of the evolution of the definition of hyperglycemia
during the past century and the alterations in glucose dynamics that cause fasting and …

Development of a standard reference material for metabolomics research

KW Phinney, G Ballihaut, M Bedner… - Analytical …, 2013 - ACS Publications
The National Institute of Standards and Technology (NIST), in collaboration with the National
Institutes of Health (NIH), has developed a Standard Reference Material (SRM) to support …

Metformin should not be used to treat prediabetes

MB Davidson - Diabetes Care, 2020 - Am Diabetes Assoc
Based on the results of the Diabetes Prevention Program Outcomes Study (DPPOS), in
which metformin significantly decreased the development of diabetes in individuals with …

Insulin sensitivity and β-cell function during early and late pregnancy in women with and without gestational diabetes mellitus

B Mittendorfer, BW Patterson, D Haire-Joshu… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE To evaluate the metabolic alterations associated with gestational diabetes
mellitus (GDM) in women with overweight or obesity. RESEARCH DESIGN AND METHODS …

[PDF][PDF] Type 2 diabetes mellitus

R Khardori - Medscape Diabetes & Endocrinology, 2013 - refp.cohlife.org
Background Type 2 diabetes mellitus consists of an array of dysfunctions characterized by
hyperglycemia and resulting from the combination of resistance to insulin action, inadequate …