Studying non-covalent drug–DNA interactions
Drug–DNA interactions have been extensively studied in the recent past. Various
techniques have been employed to decipher these interactions. DNA is a major target for a …
techniques have been employed to decipher these interactions. DNA is a major target for a …
Diorganotin (IV) complexes based on tridentate ONO ligands as potential anticancer agents
W Jiang, Q Qin, X Xiao, Y Tan - Journal of Inorganic Biochemistry, 2022 - Elsevier
Eight new diorganotin (IV) complexes (1a-2d), namely {[XC 6 H 4 (O) C= NN= C (Me) COO]
R 2 Sn (CH 3 OH)} n (1a, 2a),{[XC 6 H 4 (O) C= NN= C (Me) COO] R 2 Sn (CH 3 OH)} 2 (1b …
R 2 Sn (CH 3 OH)} n (1a, 2a),{[XC 6 H 4 (O) C= NN= C (Me) COO] R 2 Sn (CH 3 OH)} 2 (1b …
BSA/HAS interaction and antioxidant evaluation of newly synthesized benzoxazine Derivatives: Spectrophotometric and molecular docking studies
SR Sangani, Y Yao, RC Dabhi, M Kawad… - Journal of Molecular …, 2023 - Elsevier
BSA and HSA binding activity of recently reported benzoxazine derivatives (BD) was studied
at 298.15 K with UV/Vis, fluorescence spectrophotometric and docking analysis. In …
at 298.15 K with UV/Vis, fluorescence spectrophotometric and docking analysis. In …
Synthesis, structure, DNA/BSA binding, antibacterial and molecular docking studies of tetradentate ONNO schiff base metal complexes
A Salomanravi, P Muthuselvan… - Journal of Molecular …, 2023 - Elsevier
A new Schiff base ligand 3-bis ((E)-2 hydroxy-3-methoxybenzylidene) amino) malononitrile
was synthesized by combining O-vanillin and 2, 3-diaminomaleonitrile. This ligand was …
was synthesized by combining O-vanillin and 2, 3-diaminomaleonitrile. This ligand was …
Synthesis, molecular docking and DNA binding studies of phthalimide-based copper (II) complex: In vitro antibacterial, hemolytic and antioxidant assessment
In the present research work, we prepared N-substituted phthalimide, 2-(-(2-(2-(2-(1, 3-
dioxoisoindoline-2-yl-ethylamino) ethylamino) ethyl) isoindoline-1, 3-dione (DEEI) and its …
dioxoisoindoline-2-yl-ethylamino) ethylamino) ethyl) isoindoline-1, 3-dione (DEEI) and its …
A couple of antitumor Pd (II) complexes make DNA-refolding and HSA-unfolding: Experimental and docking studies
M Dustkami, H Mansouri-Torshizi, K Abdi… - Journal of Molecular …, 2022 - Elsevier
Two novel Pd (II) complexes,[Pd (pn)(SA)](I) and [Pd (pn)(SSA)](II)) pn= propylenediamine,
SA= salicylate and SSA= sulfosalicylate (were made and characterized by spectroscopic …
SA= salicylate and SSA= sulfosalicylate (were made and characterized by spectroscopic …
Synthesis, DNA Binding, and Molecular Docking Studies of Dimethylaminobenzaldehyde‐Based Bioactive Schiff Bases
ZM Almarhoon, WA Al-Onazi, AA Alothman… - Journal of …, 2019 - Wiley Online Library
A new series of p‐dimethylaminobenzaldehyde derivatives were tested for therapeutic
potential by exploring their properties through characterization. The derivatives were …
potential by exploring their properties through characterization. The derivatives were …
Synthesis and structural characterization of ternary Cu (II) complexes of glycine with 2, 2′-bipyridine and 2, 2′-dipyridylamine. The DNA-binding studies and …
MS Mohamed, AA Shoukry, AG Ali - Spectrochimica Acta Part A: Molecular …, 2012 - Elsevier
In this study two new complexes [Cu (bpy)(Gly) Cl]· 2H2O (1) and [Cu (dpa)(Gly) Cl]· 2H2O
(2)(bpy= 2, 2′-bipyridine; dpa= 2, 2′-dipyridylamine, Gly= glycine) have been synthesized …
(2)(bpy= 2, 2′-bipyridine; dpa= 2, 2′-dipyridylamine, Gly= glycine) have been synthesized …
Direct evidences for the groove binding of the Clomifene to double stranded DNA
It has been reported that the antiestrogen Tamoxifen induces liver tumors in rats and
genotoxic effects in vitro through DNA interaction. So, it can be proposed that its structural …
genotoxic effects in vitro through DNA interaction. So, it can be proposed that its structural …
Preparation of a highly stable drug carrier by efficient immobilization of human serum albumin (HSA) on drug-loaded magnetic iron oxide nanoparticles
NH Moghadam, S Salehzadeh, J Rakhtshah… - International journal of …, 2019 - Elsevier
Albumin immobilized nanoparticles are known to be biodegradable, easy to prepare and
reproducible for drug delivery systems. In summary, we have synthesized a new drug carrier …
reproducible for drug delivery systems. In summary, we have synthesized a new drug carrier …