The vascular endothelium is an interface between the blood stream and the vessel wall.
Changes in this single cell layer of the artery wall are believed of primary importance in the …

Early atherosclerosis features functional and structural changes in the endothelial barrier
function that affect the traffic of molecules and solutes between the vessel lumen and the …

The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is
primarily conformed of glycoproteins and proteoglycans, which provide communication …

Cells are covered by a surface layer of glycans that is referred to as the 'glycocalyx'. In this
review, we focus on the role of the glycocalyx in vascular diseases (atherosclerosis, stroke …

Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

The endothelial glycocalyx is an important part of the vascular barrier. The glycocalyx is
intimately linked to the homoeostatic functions of the endothelium. Damage to the glycocalyx …

Endothelial cells line the inner portion of the heart, blood vessels, and lymphatic vessels; a
basal membrane of extracellular matrix lines the extraluminal side of endothelial cells. The …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

This review aims at presenting state-of-the-art knowledge on the composition and functions
of the endothelial glycocalyx. The endothelial glycocalyx is a network of membrane-bound …

Glycosaminoglycans (GAGs) as one major part of the glycocalyx are involved in many
essential biological cell processes, as well as in many courses of diseases. Because of the …