Orthopedic surgeons face a lot of difficulties in managing and repairing osteochondral
defects. Damaged articular cartilage and the subchondral bone underneath are both present …

In recent years, the realm of tissue regeneration experienced significant advancements,
leading to the development of innovative therapeutic agents. The systemic delivery of …

Organ and tissue dysfunction represents a clinically significant condition. By integrating cell
biology with materials science, tissue engineering enables the reconstruction and …

The entry of subcutaneous extracellular matrix proteins into the circulation is a key step in
hemostasis initiation after vascular injury. However, in cases of severe trauma, extracellular …

Background: The cartilage tissue lacks blood vessels, which is composed of chondrocytes
and ECM. Due to this vessel-less structure, it is difficult to repair cartilage tissue damages …

The overall burden associated with musculoskeletal (MSK) conditions surpasses that of
tobacco-related health effects, cancer, and diabetes (Barbour et al., 2017; United States …

We investigated the fracture behavior of cellulose nanofiber (CNF)-reinforced poly (vinyl
alcohol)(PVA) hydrogels cross-linked with borax and the effect of freeze–thaw (FT) cycles on …

Background: In the domain of plastic surgery, nasal cartilage regeneration is of significant
importance. The extracellular matrix (ECM) from porcine nasal septum cartilage has shown …

The curdlan gel is a natural material produced by bacteria. It utilizes chemical cross-linking
reactions to form a 3D porous composite hydrogel, increasing its porosity and water content …

Conventional methods have failed to show the ability of articular cartilage to completely
restore. Decellularized extracellular matrix has achieved interest as a potential biomaterial …