Podocytopathies

JB Kopp, HJ Anders, K Susztak, MA Podestà… - Nature Reviews …, 2020 - nature.com
Podocytopathies are kidney diseases in which direct or indirect podocyte injury drives
proteinuria or nephrotic syndrome. In children and young adults, genetic variants in> 50 …

Epidemiology of IgA nephropathy: a global perspective

FP Schena, I Nistor - Seminars in nephrology, 2018 - Elsevier
IgA nephropathy (IgAN), or Berger's disease, is the most common primary glomerular
disease worldwide, but varies largely in its geographic distribution. A systematic review of …

Renal biopsy in 2015-from epidemiology to evidence-based indications

M Fiorentino, D Bolignano, V Tesar, A Pisano… - American journal of …, 2016 - karger.com
Background: Although the number of patients reaching end-stage kidney disease without a
biopsy-proven diagnosis is increasing, the utility of renal biopsy is still an object of debate …

Hematuria and proteinuria

HK Yap, PYW Lau - Pediatric kidney disease, 2023 - Springer
Hematuria or proteinuria may be just a normal transient finding in children, usually
accompanying a non-specific viral infection, or it can be an indicator of a kidney or urinary …

Pathogenic Role of MicroRNA Dysregulation in Podocytopathies

F Liu, J Chen, C Luo, X Meng - Frontiers in Physiology, 2022 - frontiersin.org
MicroRNAs (miRNAs) participate in the regulation of various important biological processes
by regulating the expression of various genes at the post-transcriptional level …

The difficulty in considering modifiable pathology risk factors in children with IgA nephropathy: crescents and timing of renal biopsy

R Coppo, JC Davin - Pediatric nephrology, 2015 - Springer
The need for an early diagnosis of primary IgA nephropathy (IgAN) is particularly felt in
children since they have a long life expectancy. However, IgAN has a slowly progressive …

Renal histological features of school‐age children with asymptomatic haematuria and/or proteinuria: A multicenter study

Y Zhai, H Xu, Q Shen, Q Cao, G Zhu, M Wei, L Sun… - …, 2014 - Wiley Online Library
Aim The risk of asymptomatic haematuria and/or proteinuria development into chronic
progressive glomerulonephritis (CPG) is unclear. The indications for renal biopsy and follow …

Controversy between biopsy and risk in children with proteinuria: is there a paradigm war?

J Yang, X Liu - BMC nephrology, 2024 - Springer
Background Proteinuria is a prevalent symptom of pediatric nephrology, while kidney biopsy
remains the gold standard for kidney tissue analysis, and it is currently controversial. We …

Differentialdiagnose der Hämaturie und Proteinurie

R Beetz, M Stehr, M Fisch - Die Kinder-und Jugendurologie, 2023 - Springer
Hämaturie und Proteinurie finden sich bei zahlreichen Nieren-und Harnwegserkrankungen,
können aber auch als Zufallsbefund in der Routine-Untersuchung bei sonst gesunden …

Clinical, pathological, and genetic characteristics of cases with asymptomatic proteinuria not manifesting nephrotic syndrome at onset: a single-center retrospective …

Y Watanabe, S Fujinaga, K Sakuraya, H Ikeda… - Clinical and …, 2022 - Springer
Background Cases with asymptomatic proteinuria (ASP) not manifesting nephrotic
syndrome often pathologically show focal segmental glomerulosclerosis (FSGS). However …