This review provides an overview of the current methods for quantifying mitochondrial
ultrastructure, including cristae morphology, mitochondrial contact sites, and recycling …

Each organelle referring to a complex multiorder architecture executes respective biological
processes via its distinct spatial organization and internal microenvironment. As the …

The hallmarks of aging have been influential in guiding the biology of aging research, with
more recent and growing recognition of the interdependence of these hallmarks on age …

The presence of membrane-bound organelles with specific functions is one of the main
hallmarks of eukaryotic cells. Organelle membranes are composed of specific lipids that …

Mitochondria rely on coordinated expression of their own mitochondrial DNA (mtDNA) with
that of the nuclear genome for their biogenesis. The bacterial ancestry of mitochondria has …

Cell homeostasis and function rely on well-orchestrated communication between different
organelles. This communication is ensured by signaling pathways and membrane contact …

Mitochondrial membranes are defined by their diverse functions, complex geometries, and
unique lipidomes. In the inner mitochondrial membrane (IMM), highly-curved membrane …

Organelles are specialized areas where cells perform specific processes necessary for life
and actively communicate with each other to keep the whole cell functioning. Disorders of …

Neurodegenerative diseases encompass a spectrum of conditions characterized by the
gradual deterioration of neurons in the central and peripheral nervous system. While their …

The molecular basis for bulk autophagy activation due to a deficiency in essential nutrients
such as carbohydrates, amino acids, and nitrogen is well understood. Given autophagy …