Unlocking hidden potential: advancements, approaches, and obstacles in repurposing drugs for cancer therapy

FR Weth, GB Hoggarth, AF Weth, E Paterson… - British Journal of …, 2024 - nature.com
High rates of failure, exorbitant costs, and the sluggish pace of new drug discovery and
development have led to a growing interest in repurposing “old” drugs to treat both common …

Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug delivery applications

M Pourmadadi, MM Eshaghi, S Ostovar… - Journal of Drug Delivery …, 2023 - Elsevier
The emergence of nanomedicine drugs as a result of the fast advancement of
nanotechnology offers enormous potential for improving cancer treatment strategies. The …

Liposomal doxorubicin as targeted delivery platform: Current trends in surface functionalization

V Makwana, J Karanjia, T Haselhorst… - International Journal of …, 2021 - Elsevier
Liposomal delivery systems have significantly enhanced the efficacy and safety of
chemotherapeutic agents compared to free (non-liposomal) formulations. Liposomes are …

Inhalable resveratrol-cyclodextrin complex loaded biodegradable nanoparticles for enhanced efficacy against non-small cell lung cancer

X Wang, V Parvathaneni, SK Shukla… - International Journal of …, 2020 - Elsevier
Resveratrol (RES), a natural polyphenol in fruits, has shown promising anti-cancer
properties. Due to its relative low toxicity which limits the adverse effects observed for …

Inhalation delivery of repurposed drugs for lung cancer: approaches, benefits and challenges

P Kumbhar, A Manjappa, R Shah, NK Jha… - Journal of Controlled …, 2022 - Elsevier
Lung cancer (LC) is one of the leading causes of mortality accounting for almost 25% of
cancer deaths throughout the world. The shortfall of affordable and effective first-line …

Preparation of Drug‐Loaded Albumin Nanoparticles and Its Application in Cancer Therapy

R Meng, H Zhu, Z Wang, S Hao… - Journal of …, 2022 - Wiley Online Library
Albumin is derived from plasma and it is the most abundant protein in plasma, which is an
ideal material for the preparation of nanoparticles because of its good biocompatibility …

Recent advancement on albumin nanoparticles in treating lung carcinoma

Sristi, M Fatima, A Sheikh, WH Almalki… - Journal of Drug …, 2023 - Taylor & Francis
With the advancement of nanotechnology, many different forms of nanoparticles (NPs) are
created, which specifically enhance anticancer drug delivery to tumour cells. Albumin bio …

[HTML][HTML] Scalable production and in vitro efficacy of inhaled erlotinib nanoemulsion for enhanced efficacy in non-small cell lung cancer (NSCLC)

G Chauhan, X Wang, C Yousry, V Gupta - Pharmaceutics, 2023 - mdpi.com
Non-small cell lung cancer (NSCLC) is a global concern as one of the leading causes of
cancer deaths. The treatment options for NSCLC are limited to systemic chemotherapy …

Photoredox-Catalyzed Cascade sp2 C–H Bond Functionalization to Construct Substituted Acridine with Diarylamine and Hypervalent Iodine(III) Reagents

L Liu, Y Zhang, W Zhao, J Wen, C Dong, C Hu… - Organic Letters, 2023 - ACS Publications
A photocatalyzed cascade double C–C formation via sp2 C–H bond activation of
diarylamines with hypervalent iodine diazo reagents was developed. A variety of …