Bone fragility is a major health concern, as the increased risk of bone fractures has
devastating outcomes in terms of mortality, decreased autonomy, and healthcare costs …

Being able to predict the mechanical properties of vertebrae in patients with osteoporosis
and other relevant pathologies is essential to prevent fractures and to develop the most …

Finite element analysis of computed tomography (CT) scans provides noninvasive estimates
of bone strength at the spine and hip. To further validate such estimates clinically, we …

PURPOSE: Femoral fracture is a common medical problem in osteoporotic individuals. Bone
mineral density (BMD) is the gold standard measure to evaluate fracture risk in vivo …

In this paper, we review analytical and computational models of bone fracture and strength.
Bone fracture is a complex phenomenon due to the composite, inhomogeneous and …

Data on treatment of glucocorticoid‐induced osteoporosis (GIO) in men are scarce. We
performed a randomized, open‐label trial in men who have taken glucocorticoids (GC) for≥ …

Abstract The International Society for Clinical Densitometry (ISCD) has developed new
official positions for the clinical use of quantitative computed tomography (QCT)-based finite …

Background Finite element modeling of human bone provides a powerful tool to evaluate a
wide variety of outcomes in a highly repeatable and parametric manner. These models are …

Accurate measurement of local strain in heterogeneous and anisotropic bone tissue is
fundamental to understand the pathophysiology of musculoskeletal diseases, to evaluate …

Based on spiral 3D tomography a large variety of applications have been developed during
the last decade to asses bone mineral density, bone macro and micro structure, and bone …