The bioluminescence signal generated by the luciferase-luciferin interaction, exploited for
real-time and continuous monitoring of numerous biochemical processes in living cells and …

The interaction between renal intrinsic cells and macrophages plays a crucial role in the
onset and progression of kidney diseases. In recent years, epigenetic mechanisms such as …

X chromosome inactivation (XCI) generates clonal heterogeneity within XX individuals.
Combined with sequence variation between human X chromosomes, XCI gives rise to intra …

Mammarenavirus are a large family of enveloped negative-strand RNA viruses that include
several agents responsible for severe hemorrhagic fevers. Until now, no FDA-licensed drug …

Duchenne muscular dystrophy (DMD) is an X-linked disorder caused by loss of function
mutations in the dystrophin gene (Dmd), resulting in progressive muscle weakening. Here …

Aryl hydrocarbon receptor (AHR) signalling integrates biological processes that sense and
respond to environmental, dietary, and metabolic challenges to ensure tissue homeostasis …

The naturally occurring phenomenon of bioluminescence has intrigued on-lookers for
decades and is now being developed as a powerful tool for medical research and preclinical …

Synthetic genetic biosensors that can operate at the transcriptional and translation levels
have been widely applied in the control of cellular behaviors and functions. However, the …

CD8+ T cells play a critical role during adaptive immune response, which often change
locations and expand or contract in numbers under different states. In the past, many …

Bioluminescence imaging (BLI) in rodent models has revolutionized preclinical research in
recent decades, enabling precise and noninvasive observation of cellular and molecular …