P Golforoush, DM Yellon, SM Davidson - Basic research in cardiology, 2020 - Springer
Atherosclerotic plaques impair vascular function and can lead to arterial obstruction and tissue ischaemia. Rupture of an atherosclerotic plaque within a coronary artery can result in …
DFD Mahmood, A Abderrazak, K El Hadri… - Antioxidants & redox …, 2013 - liebertpub.com
The thioredoxin (Trx) system comprises Trx, truncated Trx (Trx-80), Trx reductase, and NADPH, besides a natural Trx inhibitor, the thioredoxin-interacting protein (TXNIP). This …
MA Sussman, M Völkers, K Fischer… - Physiological …, 2011 - journals.physiology.org
One of the greatest examples of integrated signal transduction is revealed by examination of effects mediated by AKT kinase in myocardial biology. Positioned at the intersection of …
Diet-induced hypercholesterolemia leads to oxidative/nitrative stress and subsequent myocardial dysfunction. However, the regulatory role of microRNAs in this phenomenon is …
Hypercholesterolemia is a frequent metabolic disorder associated with increased risk for cardiovascular morbidity and mortality. In addition to its well‐known proatherogenic effect …
The morbidity and mortality from cardiovascular diseases (CVD) remain high. Metabolic diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …
I Andreadou, R Schulz, L Badimon… - British journal of …, 2020 - Wiley Online Library
Hyperlipidaemia is a well‐established risk factor for cardiovascular diseases and therefore, many animal model have been developed to mimic the human abnormal elevation of blood …
Y Chtourou, AB Slima, M Makni, R Gdoura… - Pharmacological …, 2015 - Springer
Background In earlier studies, the supplementation of the natural compound Naringenin (NGEN), improved the liver oxidative and inflammatory status, which indicates its direct effect …
Hypercholesterolaemia is considered to be a principle risk factor for cardiovascular disease, having direct negative effects on the myocardium itself, in addition to the development of …