Advances in norovirus biology

SM Karst, CE Wobus, IG Goodfellow, KY Green… - Cell host & …, 2014 - cell.com
Human noroviruses are a major cause of epidemic and sporadic gastroenteritis worldwide
and can chronically infect immunocompromised patients. Efforts to develop effective …

Emergence of norovirus strains: A tale of two genes

GI Parra - Virus Evolution, 2019 - academic.oup.com
Noroviruses are a very diverse group of viruses that infect different mammalian species. In
humans, norovirus is a major cause of acute gastroenteritis. Multiple norovirus infections can …

Recombination within the pandemic norovirus GII. 4 lineage

JS Eden, MM Tanaka, MF Boni, WD Rawlinson… - Journal of …, 2013 - Am Soc Microbiol
Norovirus (NoV) is the leading cause of viral gastroenteritis globally. Since 1996, NoV
variants of a single genetic lineage, GII. 4, have been associated with at least six pandemics …

Immunogenetic mechanisms driving norovirus GII. 4 antigenic variation

LC Lindesmith, M Beltramello, EF Donaldson… - PLoS …, 2012 - journals.plos.org
Noroviruses are the principal cause of epidemic gastroenteritis worldwide with GII. 4 strains
accounting for 80% of infections. The major capsid protein of GII. 4 strains is evolving …

[HTML][HTML] Evolution of norovirus

PA White - Clinical Microbiology and Infection, 2014 - Elsevier
Norovirus (NoV) is now the dominant aetiological agent of acute gastroenteritis, and, with
the recent introduction of rotavirus vaccines in many countries, this is likely to remain the …

[HTML][HTML] Pathogenesis of noroviruses, emerging RNA viruses

SM Karst - Viruses, 2010 - mdpi.com
Human noroviruses in the family Caliciviridae are a major cause of epidemic gastroenteritis.
They are responsible for at least 95% of viral outbreaks and over 50% of all outbreaks …

Emergence of new pandemic GII. 4 Sydney norovirus strain correlates with escape from herd immunity

K Debbink, LC Lindesmith… - The Journal of …, 2013 - academic.oup.com
Background. GII. 4 noroviruses are a significant source of acute gastroenteritis worldwide,
causing the majority of human norovirus outbreaks. Evolution of the GII. 4 major capsid …

Chitosan: a promising safe and immune-enhancing adjuvant for intranasal vaccines

A Smith, M Perelman, M Hinchcliffe - Human vaccines & …, 2014 - Taylor & Francis
The nasal route is attractive for the delivery of vaccines in that it not only offers an easy to
use, non-invasive, needle-free alternative to more conventional parenteral injection, but it …

Emergence of a norovirus GII. 4 strain correlates with changes in evolving blockade epitopes

LC Lindesmith, V Costantini, J Swanstrom… - Journal of …, 2013 - Am Soc Microbiol
The major capsid protein of norovirus GII. 4 strains is evolving rapidly, resulting in epidemic
strains with altered antigenicity. GII. 4.2006 Minerva strains circulated at pandemic levels in …

Genetic mapping of a highly variable norovirus GII. 4 blockade epitope: potential role in escape from human herd immunity

K Debbink, EF Donaldson, LC Lindesmith… - Journal of …, 2012 - Am Soc Microbiol
Noroviruses account for 96% of viral gastroenteritis cases worldwide, with GII. 4 strains
responsible> 80% of norovirus outbreaks. Histo-blood group antigens (HBGAs) are …