Principles of actomyosin regulation in vivo

P Agarwal, R Zaidel-Bar - Trends in Cell Biology, 2019 - cell.com
The actomyosin cytoskeleton is responsible for most force-driven processes in cells and
tissues. How it assembles into the necessary structures at the right time and place is an …

Stretch-induced actomyosin contraction in epithelial tubes: Mechanotransduction pathways for tubular homeostasis

K Sethi, EJ Cram, R Zaidel-Bar - Seminars in cell & developmental biology, 2017 - Elsevier
Many tissues in our body have a tubular shape and are constantly exposed to various
stresses. Luminal pressure imposes tension on the epithelial and myoepithelial or smooth …

Cell and tissue mechanics: the new cell biology frontier

VM Weaver - Molecular biology of the cell, 2017 - Am Soc Cell Biol
All living organisms experience force (Figure 1). These forces exist at the nanoscale level
through to the tissue level and range from piconewtons upward to several orders of …

Cellular expression and functional roles of all 26 neurotransmitter GPCRs in the C. elegans egg-laying circuit

RW Fernandez, K Wei, EY Wang… - Journal of …, 2020 - Soc Neuroscience
Maps of the synapses made and neurotransmitters released by all neurons in model
systems, such as Caenorhabditis elegans have left still unresolved how neural circuits …

Crosslinking activity of non-muscle myosin II is not sufficient for embryonic cytokinesis in C. elegans

DS Osório, FY Chan, J Saramago, J Leite… - …, 2019 - journals.biologists.com
Cytokinesis in animal cells requires the assembly and constriction of a contractile
actomyosin ring. Non-muscle myosin II is essential for cytokinesis, but the role of its motor …

[HTML][HTML] Theory of active self-organization of dense nematic structures in the actin cytoskeleton

W Mirza, M De Corato, M Pensalfini, G Vilanova… - eLife, 2024 - elifesciences.org
The actin cytoskeleton is remarkably adaptable and multifunctional. It often organizes into
nematic bundles such as contractile rings or stress fibers. However, how a uniform and …

Spectrin regulates cell contractility through production and maintenance of actin bundles in the Caenorhabditis elegans spermatheca

ACE Wirshing, EJ Cram - Molecular Biology of the Cell, 2018 - Am Soc Cell Biol
Disruption to the contractility of cells, including smooth muscle cells of the cardiovascular
system and myoepithelial cells of the glandular epithelium, contributes to the …

Variational formulation of active nematics: theory and simulation

W Mirza, A Torres-Sánchez, G Vilanova… - arXiv preprint arXiv …, 2023 - arxiv.org
The structure and dynamics of important biological quasi-two-dimensional systems, ranging
from cytoskeletal gels to tissues, are controlled by nematic order, defects and activity …

[HTML][HTML] Pulsed actomyosin contractions in morphogenesis

A Sutherland, A Lesko - F1000Research, 2020 - ncbi.nlm.nih.gov
Cell and tissue shape changes are the fundamental elements of morphogenesis that drive
normal development of embryos into fully functional organisms. This requires a variety of …

SRGP-1/srGAP and AFD-1/afadin stabilize HMP-1/⍺-catenin at rosettes to seal internalization sites following gastrulation in C. elegans

JM Serre, MM Slabodnick, B Goldstein, J Hardin - PLoS genetics, 2023 - journals.plos.org
A hallmark of gastrulation is the establishment of germ layers by internalization of cells
initially on the exterior. In C. elegans the end of gastrulation is marked by the closure of the …