Vaccines against mpox: MVA-BN and LC16m8

JD Grabenstein, A Hacker - Expert Review of Vaccines, 2024 - Taylor & Francis
Introduction Global outbreaks involving mpox clade IIb began in mid-2022. Today, clade IIb
and clade I outbreaks continue. Reliable mpox vaccines can prevent serious mpox disease …

[HTML][HTML] Update on Mpox: a brief narrative review

S Antinori, G Casalini, A Giacomelli… - Le Infezioni in …, 2023 - ncbi.nlm.nih.gov
Mpox (formerly Monkeypox), a neglected tropical disease once confined to Central and West
Africa, emerged as a global epidemic outbreak in May, 2022 with 87,529 cases reported as …

Mpox vaccine and infection-driven human immune signatures: an immunological analysis of an observational study

H Cohn, N Bloom, GY Cai, JJ Clark, A Tarke… - The Lancet Infectious …, 2023 - thelancet.com
Background Monkeypox virus has recently infected more than 88 000 people, raising
concerns about our preparedness against this emerging viral pathogen. Licensed and …

Multi-omics characterization of the monkeypox virus infection

Y Huang, V Bergant, V Grass, Q Emslander… - Nature …, 2024 - nature.com
Multiple omics analyzes of Vaccinia virus (VACV) infection have defined molecular
characteristics of poxvirus biology. However, little is known about the monkeypox (mpox) …

Monkeypox virus-infected individuals mount comparable humoral immune responses as Smallpox-vaccinated individuals

AD Otter, S Jones, B Hicks, D Bailey, H Callaby… - Nature …, 2023 - nature.com
In early 2022, a cluster of monkeypox virus (MPXV) infection (mpox) cases were identified
within the UK with no prior travel history to MPXV-endemic regions. Subsequently, case …

Transmission dynamics and effect of control measures on the 2022 outbreak of mpox among gay, bisexual, and other men who have sex with men in England: a …

XS Zhang, S Mandal, H Mohammed… - The Lancet Infectious …, 2024 - thelancet.com
Background The 2022 global outbreak of mpox (formerly known as monkeypox) spread
primarily among gay, bisexual, and other men who have sex with men (GBMSM), with the …

[HTML][HTML] Continued circulation of mpox: an epidemiological and phylogenetic assessment, European Region, 2023 to 2024

AM Vaughan, M Afzal, P Nannapaneni… - …, 2024 - eurosurveillance.org
During the summer of 2023, the European Region experienced a limited resurgence of
mpox cases following the substantial outbreak in 2022. This increase was characterised by …

Mpox neutralizing antibody response to LC16m8 vaccine in healthy adults

E Morino, S Mine, N Tomita, Y Uemura… - NEJM …, 2024 - evidence.nejm.org
Background Vaccination against mpox (formerly known as monkeypox), an infectious
disease caused by the monkeypox virus (MPXV), is needed to prevent outbreaks and …

[HTML][HTML] Effectiveness of historical smallpox vaccination against mpox clade II in men in Denmark, France, the Netherlands and Spain, 2022

S Colombe, S Funke, A Koch, M Haverkate… - …, 2024 - eurosurveillance.org
Background In 2022, a global monkeypox virus (MPXV) clade II epidemic occurred mainly
among men who have sex with men. Until early 1980s, European smallpox vaccination …

Predicting vaccine effectiveness for mpox

MT Berry, SR Khan, TE Schlub, A Notaras… - Nature …, 2024 - nature.com
Abstract The Modified Vaccinia Ankara vaccine developed by Bavarian Nordic (MVA-BN)
was widely deployed to prevent mpox during the 2022 global outbreak. This vaccine was …