Role of animal models in biomedical research: a review

P Mukherjee, S Roy, D Ghosh, SK Nandi - Laboratory Animal Research, 2022 - Springer
The animal model deals with the species other than the human, as it can imitate the disease
progression, its' diagnosis as well as a treatment similar to human. Discovery of a drug …

Alveolar lipids in pulmonary disease. A review

CW Agudelo, G Samaha, I Garcia-Arcos - Lipids in health and disease, 2020 - Springer
Lung lipid metabolism participates both in infant and adult pulmonary disease. The lung is
composed by multiple cell types with specialized functions and coordinately acting to meet …

Liposomal vaccine formulations as prophylactic agents: design considerations for modern vaccines

LO De Serrano, DJ Burkhart - Journal of nanobiotechnology, 2017 - Springer
Vaccinology is one of the most important cornerstones in modern medicine, providing better
quality of life. The human immune system is composed of innate and adaptive immune …

Identification and evaluation of novel protective antigens for the development of a candidate tuberculosis subunit vaccine

E Stylianou, R Harrington-Kandt, J Beglov… - Infection and …, 2018 - Am Soc Microbiol
The development of a vaccine against tuberculosis (TB), a disease caused by
Mycobacterium tuberculosis, is urgently needed. The only currently available vaccine, M …

Nanotechnology and tuberculosis: An old disease with new treatment strategies

DC dos Santos Macêdo, IDL Cavalcanti, JB de Souza… - Tuberculosis, 2022 - Elsevier
Tuberculosis is an intracellular infectious disease caused by Mycobacterium tuberculosis,
which mainly affects the lungs. Especially in patients infected by the Human …

Mathematical analysis of a tuberculosis model with imperfect vaccine

AO Egonmwan, D Okuonghae - International Journal of …, 2019 - World Scientific
Since 1921, the Bacille Calmette–Guerin (BCG) vaccine continues to be the most widely
used vaccine for the prevention of Tuberculosis (TB). However, the immunity induced by …

Lipoarabinomannan in active and passive protection against tuberculosis

M Correia-Neves, C Sundling, A Cooper… - Frontiers in …, 2019 - frontiersin.org
Glycolipids of the cell wall of Mycobacterium tuberculosis (Mtb) are important
immunomodulators in tuberculosis. In particular, lipoarabinomannan (LAM) has a profound …

The role of donor‐unrestricted T‐cells, innate lymphoid cells, and NK cells in anti‐mycobacterial immunity

P Ruibal, L Voogd, SA Joosten… - Immunological …, 2021 - Wiley Online Library
Vaccination strategies against mycobacteria, focusing mostly on classical T‐and B‐cells,
have shown limited success, encouraging the addition of alternative targets. Classically …

Application of liposomes in the treatment of infectious diseases

NAA Suhaimi, S Ahmad, SMN Husna, ME Sarmiento… - Life Sciences, 2022 - Elsevier
The advances in the development of drugs and vaccines for major infectious diseases of
tuberculosis (TB), malaria and HIV represent some of the most significant milestones in their …

Animal models for COVID-19 and tuberculosis

B Corleis, M Bastian, D Hoffmann, M Beer… - Frontiers in …, 2023 - frontiersin.org
Respiratory infections cause tremendous morbidity and mortality worldwide. Amongst these
diseases, tuberculosis (TB), a bacterial illness caused by Mycobacterium tuberculosis which …