Circadian rhythms in neurodegenerative disorders

M Nassan, A Videnovic - Nature Reviews Neurology, 2022 - nature.com
Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Positive effects of combined cognitive and physical exercise training on cognitive function in older adults with mild cognitive impairment or dementia: A meta-analysis

EGAE Karssemeijer, JAJ Aaronson, WJW Bossers… - Ageing research …, 2017 - Elsevier
Combined cognitive and physical exercise interventions have potential to elicit cognitive
benefits in older adults with mild cognitive impairment (MCI) or dementia. This meta-analysis …

Cognitive training for people with mild to moderate dementia

A Bahar‐Fuchs, A Martyr, AMY Goh… - Cochrane Database …, 2019 - cochranelibrary.com
Background Cognitive impairment, a defining feature of dementia, plays an important role in
the compromised functional independence that characterises the condition. Cognitive …

Exercise interventions in Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials

S Lopez-Ortiz, PL Valenzuela, MM Seisdedos… - Ageing Research …, 2021 - Elsevier
Aims To assess the potential multi-domain benefits of exercise interventions on patients with
Alzheimer's disease (AD), as well as to determine the specific effects of different exercise …

Circadian disruption and sleep disorders in neurodegeneration

Y Shen, Q Lv, W Xie, S Gong, S Zhuang, J Liu… - Translational …, 2023 - Springer
Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative
diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional …

Physical activity improves cognition and activities of daily living in adults with alzheimer's disease: A systematic review and meta-analysis of randomized controlled …

S Zhou, S Chen, X Liu, Y Zhang, M Zhao… - International Journal of …, 2022 - mdpi.com
Objective: The purpose of this meta-analysis was to examine the effects of physical activity
(PA) on cognition and activities of daily living in adults with Alzheimer's Disease (AD) …

Circadian rhythms of the hypothalamus: from function to physiology

R Van Drunen, K Eckel-Mahan - Clocks & sleep, 2021 - mdpi.com
The nearly ubiquitous expression of endogenous 24 h oscillations known as circadian
rhythms regulate the timing of physiological functions in the body. These intrinsic rhythms …

The quest for synergy between physical exercise and cognitive stimulation via exergaming in people with dementia: a randomized controlled trial

EGA Karssemeijer, JA Aaronson, WJR Bossers… - Alzheimer's research & …, 2019 - Springer
Background Exercise is often proposed as a non-pharmacological intervention to delay
cognitive decline in people with dementia, but evidence remains inconclusive. Previous …

Cognitive therapy for dementia patients: a systematic review

C Carrion, F Folkvord, D Anastasiadou… - Dementia and geriatric …, 2018 - karger.com
Background: Cognitive therapy is a well-established intervention for treating elderly suffering
from dementia. In particular, reality orientation and skills training seem to be effective …

Combined exercise and cognitive interventions for adults with mild cognitive impairment and dementia: A systematic review and network meta-analysis

D Xue, PWC Li, SF Doris, RSY Lin - International Journal of Nursing Studies, 2023 - Elsevier
Background Exercise and cognitive interventions are beneficial for adults with preclinical
and clinical dementia, but it is unclear whether the combination of these two components …