Influence of olive oil and its components on breast cancer: Molecular mechanisms

R Moral, E Escrich - Molecules, 2022 - mdpi.com
Breast cancer is the most frequent malignant neoplasia and a leading cause of mortality in
women worldwide. The Mediterranean diet has been proposed as a healthy dietary pattern …

The Cancer-Associated Antigens Sialyl Lewisa/x and Sda: Two Opposite Faces of Terminal Glycosylation

F Dall'Olio, M Pucci, N Malagolini - Cancers, 2021 - mdpi.com
Simple Summary The glycosyltransferase β1, 4-N-acetylgalactosaminyltransferae 2
(B4GALNT2), product of the B4GALNT2 gene is responsible for the biosynthesis of the …

New affordable methods for large-scale isolation of major olive secoiridoids and systematic comparative study of their antiproliferative/cytotoxic effect on multiple …

A Papakonstantinou, P Koumarianou… - International Journal of …, 2022 - mdpi.com
Olive oil phenols (OOPs) are associated with the prevention of many human cancers. Some
of these have been shown to inhibit cell proliferation and induce apoptosis. However, no …

Next-generation sequencing reveals altered gene expression and enriched pathways in triple-negative breast cancer cells treated with oleuropein and oleocanthal

P Karousi, CK Kontos, P Papakotsi, IK Kostakis… - Functional & Integrative …, 2023 - Springer
Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by poor
prognosis and limited treatment options. Oleuropein and oleocanthal are bioactive …

Protective effects and benefits of olive oil and its extracts on women's health

TTG Ly, J Yun, DH Lee, JS Chung, SM Kwon - Nutrients, 2021 - mdpi.com
Women and men share similar diseases; however, women have unique issues, including
gynecologic diseases and diseases related to menstruation, menopause, and post …

The story of the Sda antigen and of its cognate enzyme B4GALNT2: What is new?

M Duca, N Malagolini, F Dall'Olio - Glycoconjugate journal, 2023 - Springer
Abstract The structure Siaα2, 3 (GalNAcβ1, 4) Gal-is the epitope of the Sda antigen, which is
expressed on the erythrocytes and secretions of the vast majority of Caucasians, carried by …

[HTML][HTML] Anticancer Effects of Secoiridoids—A Scoping Review of the Molecular Mechanisms behind the Chemopreventive Effects of the Olive Tree Components …

IY Kusuma, H Habibie, MA Bahar, F Budán, D Csupor - Nutrients, 2024 - mdpi.com
The olive tree (Olea europaea) and olive oil hold significant cultural and historical
importance in Europe. The health benefits associated with olive oil consumption have been …

[HTML][HTML] The Olive Oil Phenolic S-(-)-Oleocanthal Suppresses Colorectal Cancer Progression and Recurrence by Modulating SMYD2-EZH2 and c-MET Activation

MTI Tarun, HE Elsayed, HY Ebrahim, KA El Sayed - Nutrients, 2025 - mdpi.com
Background/Objectives: Colorectal cancer (CRC) is the third most common cancer in the US
and the second leading cancer-associated mortality cause. Available CRC therapies …

[HTML][HTML] The Olive Oil Monophenolic Secoiridoid Ligstroside Aglycone Suppresses Melanoma Progression by Targeting the BRAF Signaling Pathway

MA Mahmud, AB Siddique, A Tajmim, JA King… - Molecules, 2025 - mdpi.com
Melanoma is among the most abundant malignancies in the US and worldwide. Ligstroside
aglycone (LA) is a rare extra-virgin olive oil-derived monophenolic secoiridoid with diverse …

The Sda Carbohydrate Antigen and Its Biosynthetic Enzyme B4GALNT2 in Health and Disease.

M Duca, N Malagolini, F Dall'Olio - 2024 - preprints.org
The carbohydrate antigen Sda is expressed on cells and secretions of the vast majority of
Caucasians. The epitope is formed by a terminal GalNAc residue β4-linked to a α3 …