Importance Obstructive sleep apnea (OSA) affects 17% of women and 34% of men in the US
and has a similar prevalence in other countries. This review provides an update on the …

Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA
has well established cardiovascular and neurocognitive sequelae, although the optimal …

Rationale: Data from population-based cohorts suggest that symptom subtypes and
obstructive sleep apnea (OSA)–specific hypoxic burden (HB) could help to better identify …

Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …

Excessive daytime sleepiness (EDS) is a public health issue. However, it remains largely
undervalued, scarcely diagnosed, and poorly supported. Variations in the definition of EDS …

Rationale: Recent studies suggest that obstructive sleep apnea (OSA) severity can vary
markedly from night to night, which may have important implications for diagnosis and …

One‐seventh of the world's adult population, or approximately one billion people, are
estimated to have OSA. Over the past four decades, obesity, the main risk factor for OSA, has …

Background Increased mortality has been reported in people with insomnia and in those
with obstructive sleep apnoea (OSA). However, these conditions commonly co-occur and …

Rationale: Randomized controlled trials have been unable to detect a cardiovascular benefit
of continuous positive airway pressure in unselected patients with obstructive sleep apnea …

Intermittent hypoxia (IH) is a hallmark manifestation of obstructive sleep apnea (OSA), a
widespread disorder of breathing. This Review focuses on the role of hypoxia-inducible …