Since the discovery of antioxidant responsive elements (ARE), which are commonly found in
the promoter of the Phase II metabolism/antioxidant enzymes, and nuclear factor erythroid 2 …

Triterpenoids are a powerful group of phytochemicals derived from plant foods and herbs.
Many reports have shown that they possess chemopreventive and chemotherapeutic effects …

Biological redox signaling plays an important role in many diseases. Redox signaling
involves reductive and oxidative mechanisms. Oxidative stress occurs when reductive …

Ursolic acid (UA) is a triterpenoid phytochemical with a strong anticancer effect. The
metabolic rewiring, epigenetic reprogramming, and chemopreventive effect of UA in prostate …

Triterpenic acids are phytocompounds with a widespread range of biological activities that
have been the subject of numerous in vitro and in vivo studies. However, their underlying …

Oxidative stress, an imbalance between reactive oxygen species and antioxidants, has been
seen in the pathological states of many disorders such as ischemic diseases and cancers …

DNA methylation is the most studied epigenetic mark, and it can be altered by environmental
factors. Among these factors, ultraviolet radiation (UV) is little explored within this context …

Throughout life, organisms are exposed to various exogenous and endogenous factors that
cause DNA damages and somatic mutations provoking genomic instability. At a young age …

Early detection of biomarkers in lung cancer is one of the best preventive strategies.
Although many attempts have been made to understand the early events of lung …

The skin is the organ that is most susceptible to the impact of the exposome. Located at the
interface with the external environment, it protects internal organs through the barrier …