Glomerulonephritis: immunopathogenesis and immunotherapy

HJ Anders, AR Kitching, N Leung… - Nature Reviews …, 2023 - nature.com
Abstract 'Glomerulonephritis'(GN) is a term used to describe a group of heterogeneous
immune-mediated disorders characterized by inflammation of the filtration units of the kidney …

C3 glomerulopathy: understanding an ultra‐rare complement‐mediated renal disease

AK Heiderscheit, JJ Hauer… - American Journal of …, 2022 - Wiley Online Library
Abstract C3 glomerulopathy (C3G) describes a pathologic pattern of injury diagnosed by
renal biopsy. It is characterized by the dominant deposition of the third component of …

Recurrent glomerular disease after kidney transplantation: diagnostic and management dilemmas

A Uffing, F Hullekes, LV Riella… - Clinical Journal of the …, 2021 - journals.lww.com
Recurrent glomerular disease after kidney transplant remains an important cause of allograft
failure. Many of the different entities post-transplant still suffer from incomplete knowledge on …

Recurrence of immune complex and complement-mediated membranoproliferative glomerulonephritis in kidney transplantation

F Caravaca-Fontán, N Polanco… - Nephrology Dialysis …, 2023 - academic.oup.com
Introduction Membranoproliferative glomerulonephritis (MPGN) represents a histologic
pattern of glomerular injury that may be due to several aetiologies. Few studies have …

C3 glomerulopathies: dense deposit disease and C3 glomerulonephritis

C Ponticelli, M Calatroni, G Moroni - Frontiers in Medicine, 2023 - frontiersin.org
Dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are types of
membranoproliferative glomerulonephritis classified as C3 glomerulopathies. These …

Recurrent C3 glomerulopathy after kidney transplantation

S Obata, PASV de Castro, LV Riella, P Cravedi - Transplantation Reviews, 2024 - Elsevier
The complement system is part of innate immunity and is pivotal in protecting the body
against pathogens and maintaining host homeostasis. Activation of the complement system …

Antibody-mediated rejection and recurrent primary disease: two main obstacles in abdominal kidney, liver, and pancreas transplants

T Nakamura, T Shirouzu - Journal of Clinical Medicine, 2021 - mdpi.com
The advances in acute phase care have firmly established the practice of organ
transplantation in the last several decades. Then, the next issues that loom large in the field …

Updates on C3 Glomerulopathy in Kidney Transplantation: Pathogenesis and Treatment Options

G Bartoli, A Dello Strologo, G Grandaliano… - International Journal of …, 2024 - mdpi.com
C3 glomerulopathy is a rare disease, characterized by an abnormal activation of the
complement's alternative pathway that leads to the accumulation of the C3 component in the …

Recurrent C3 Glomerulonephritis along with BK-Virus-Associated Nephropathy after Kidney Transplantation: A Case Report

JH Lim, SW Shin, MS Kim, MH Han, YJ Kim, HY Jung… - Medicina, 2023 - mdpi.com
C3 glomerulonephritis (C3GN) is a rare cause of end-stage kidney disease and frequently
recurrent in allografts following kidney transplantation (KT). Herein, we describe the case of …

Kidney Transplantation in Multiple Myeloma and Monoclonal Gammopathy of Renal Significance

N Leung, C Heybeli - Seminars in Nephrology, 2024 - Elsevier
Recent advances in the treatment of plasma cell disorders (PCDs) have provided a wealth of
therapy alternatives and improved overall survival tremendously. Various types of PCDs are …