The origin of asymmetry: early polarisation of the Drosophila germline cyst and oocyte
JR Huynh, D St Johnston - Current Biology, 2004 - cell.com
The anterior–posterior axis of Drosophila is established before fertilisation when the oocyte
becomes polarised to direct the localisation of bicoid and oskar mRNAs to opposite poles of …
becomes polarised to direct the localisation of bicoid and oskar mRNAs to opposite poles of …
Checking your breaks: surveillance mechanisms of meiotic recombination
A Hochwagen, A Amon - Current Biology, 2006 - cell.com
Numerous DNA double-strand breaks (DSBs) are introduced into the genome in the course
of meiotic recombination. This poses a significant hazard to the genomic integrity of the cell …
of meiotic recombination. This poses a significant hazard to the genomic integrity of the cell …
Origins and evolution of the recA/RAD51 gene family: Evidence for ancient gene duplication and endosymbiotic gene transfer
The bacterial recA gene and its eukaryotic homolog RAD51 are important for DNA repair,
homologous recombination, and genome stability. Members of the recA/RAD51 family have …
homologous recombination, and genome stability. Members of the recA/RAD51 family have …
[HTML][HTML] Drosophila rasiRNA pathway mutations disrupt embryonic axis specification through activation of an ATR/Chk2 DNA damage response
C Klattenhoff, DP Bratu, N McGinnis-Schultz… - Developmental cell, 2007 - cell.com
Small repeat-associated siRNAs (rasiRNAs) mediate silencing of retrotransposons and the
Stellate locus. Mutations in the Drosophila rasiRNA pathway genes armitage and aubergine …
Stellate locus. Mutations in the Drosophila rasiRNA pathway genes armitage and aubergine …
Distinct DNA-damage-dependent and-independent responses drive the loss of oocytes in recombination-defective mouse mutants
M Di Giacomo, M Barchi, F Baudat… - Proceedings of the …, 2005 - National Acad Sciences
Defects in meiotic recombination in many organisms result in arrest because of activation of
a meiotic checkpoint (s). The proximal defect that triggers this checkpoint in mammalian …
a meiotic checkpoint (s). The proximal defect that triggers this checkpoint in mammalian …
Frequent and efficient use of the sister chromatid for DNA double-strand break repair during budding yeast meiosis
T Goldfarb, M Lichten - PLoS biology, 2010 - journals.plos.org
Recombination between homologous chromosomes of different parental origin (homologs)
is necessary for their accurate segregation during meiosis. It has been suggested that …
is necessary for their accurate segregation during meiosis. It has been suggested that …
FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers
C Girard, W Crismani, N Froger, J Mazel… - Nucleic acids …, 2014 - academic.oup.com
Genetic recombination is important for generating diversity and to ensure faithful
segregation of chromosomes at meiosis. However, few crossovers (COs) are formed per …
segregation of chromosomes at meiosis. However, few crossovers (COs) are formed per …
Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila
Y Chen, A Pane, T Schüpbach - Current Biology, 2007 - cell.com
Gametogenesis is a highly regulated process in all organisms. In Drosophila, a meiotic
checkpoint which monitors double-stranded DNA breaks and involves Drosophila ATR and …
checkpoint which monitors double-stranded DNA breaks and involves Drosophila ATR and …
[HTML][HTML] An essential role of DmRad51/SpnA in DNA repair and meiotic checkpoint control
E Staeva‐Vieira, S Yoo, R Lehmann - The EMBO Journal, 2003 - embopress.org
Rad51 is a conserved protein essential for recombinational repair of double‐stranded DNA
breaks (DSBs) in somatic cells and during meiosis in germ cells. Yeast Rad51 mutants are …
breaks (DSBs) in somatic cells and during meiosis in germ cells. Yeast Rad51 mutants are …
Temporal Analysis of Meiotic DNA Double-Strand Break Formation and Repair in Drosophila Females
S Mehrotra, KS McKim - PLoS genetics, 2006 - journals.plos.org
Using an antibody against the phosphorylated form of His2Av (γ-His2Av), we have
described the time course for the series of events leading from the formation of a double …
described the time course for the series of events leading from the formation of a double …