The 2H solid-state NMR spectra of deuterated fatty acyl chains provide direct access to the
order of the hydrophobic membrane interior. From the deuterium order parameter profiles of …

Pulsed ESR techniques with the aid of site-directed spin labeling have proven useful in
providing unique structural information about proteins. The determination of distance …

The present study describes leucine zipper peptide–lipid hybrid nanoscale vesicles
engineered by self-assembled anchoring of the amphiphilic peptide within the lipid bilayer …

Shallow electron spin echo envelope modulations due to dipole–dipole couplings between
electron spins provide information on the radial distribution function of the spins in …

We have investigated the effect of a series of hydrophobic polypeptides (WALP peptides) on
the mean hydrophobic thickness of (chain-perdeuterated) phosphatidylcholines (PCs) with …

Electron paramagnetic resonance (EPR) spectroscopy is one the few methods that can
characterize structural features in the range between 0.5 and 5 nm in systems that lack long …

Tikhonov regularization is the most commonly used method for extracting distance
distributions from experimental double electron-electron resonance (DEER) spectroscopy …

The interaction of antimicrobial peptides (AMPs) with the inner membrane of Gram-negative
bacteria is a key determinant of their abilities to exert diverse bactericidal effects. Here we …

Cationic amphipathic α-helical peptides preferentially disrupt anionic lipids in mixed model
membranes, potentially causing a catastrophic release of the cell contents or attenuation of …

Designed histidine-rich amphipathic cationic peptides, such as LAH4, have enhanced
membrane disruption and antibiotic properties when the peptide adopts an alignment …